Efficacy and Mechanism Evaluation

Volume 7 (2020)

10 issues

Extended Research Article

Stratifying risk of infection and response to therapy in patients with myeloma: a prognostic study

Ilaria J Chicca
,
Jennifer LJ Heaney
,
Gulnaz Iqbal
,
Janet A Dunn
,
Stella Bowcock
,
Tim Planche
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 10
  • Published:
    8 December 2020

Extended Research Article

Ursodeoxycholic acid to reduce adverse perinatal outcomes for intrahepatic cholestasis of pregnancy: the PITCHES RCT

Lucy C Chappell
,
Jennifer L Bell
,
Anne Smith
,
Catherine Rounding
,
Ursula Bowler
,
Louise Linsell
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 9
  • Published:
    3 December 2020

Extended Research Article

Mini-combined test compared with NICE guidelines for early risk-assessment for pre-eclampsia: the SPREE diagnostic accuracy study

Liona C Poon
,
David Wright
,
Steve Thornton
,
Ranjit Akolekar
,
Peter Brocklehurst
,
Kypros H Nicolaides
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 8
  • Published:
    19 November 2020

Extended Research Article

Gabapentin to reduce pain in women aged between 18 and 50 years with chronic pelvic pain: the GaPP2 RCT

Catherine A Hewitt
,
Katy Vincent
,
Lee J Middleton
,
Liana Romaniuk
,
Magda Koscielniak
,
Ann M Doust
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 7
  • Published:
    19 November 2020

Extended Research Article

A duodenal sleeve bypass device added to intensive medical therapy for obesity with type 2 diabetes: a RCT

Aruchuna Ruban
,
Michael A Glaysher
,
Alexander D Miras
,
Anthony P Goldstone
,
Christina G Prechtl
,
Nicholas Johnson
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 6
  • Published:
    12 November 2020

Extended Research Article

Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT

Peter J McCartney
,
Hany Eteiba
,
Annette M Maznyczka
,
Margaret McEntegart
,
John P Greenwood
,
Douglas F Muir
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 5
  • Published:
    10 November 2020

Extended Research Article

Spironolactone to improve exercise tolerance in people with permanent atrial fibrillation and preserved ejection fraction: the IMPRESS-AF RCT

Eduard Shantsila
,
Farhan Shahid
,
Yongzhong Sun
,
Jonathan J Deeks
,
Ronnie Haynes
,
Melanie Calvert
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 4
  • Published:
    20 July 2020

Extended Research Article

Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

Floriana De Angelis
,
Peter Connick
,
Richard A Parker
,
Domenico Plantone
,
Anisha Doshi
,
Nevin John
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 3
  • Published:
    22 May 2020

Extended Research Article

Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer's disease: the MADE Phase II, three-arm RCT

Robert Howard
,
Olga Zubko
,
Richard Gray
,
Rosie Bradley
,
Emma Harper
,
Linda Kelly
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 2
  • Published:
    24 April 2020

Extended Research Article

Positron emission tomography to image cerebral neuroinflammation in ischaemic stroke: a pilot study

Eszter Visi
,
Rainer Hinz
,
Martin Punter
,
Arshad Majid
,
Alexander Gerhard
,
Karl Herholz
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 7, Issue: 1
  • Published:
    6 February 2020