Efficacy and Mechanism Evaluation

Volume 6 (2019)

13 issues

Extended Research Article

Identifying and treating high blood pressure in men under 55 years with grade 1 hypertension: the TREAT CASP study and RCT

Bryan Williams
,
Ewan McFarlane
,
Dawid Jedrzejewski
,
Peter S Lacy
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 13
  • Published:
    19 December 2019

Extended Research Article

Platelet-rich plasma injection for adults with acute Achilles tendon rupture: the PATH-2 RCT

Joseph Alsousou
,
David J Keene
,
Paul Harrison
,
Philippa Hulley
,
Susan Wagland
,
Jacqueline Y Thompson
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 12
  • Published:
    18 December 2019

Extended Research Article

Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT

Rima K Dhillon-Smith
,
Lee J Middleton
,
Kirandeep K Sunner
,
Versha Cheed
,
Krys Baker
,
Samantha Farrell-Carver
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 11
  • Published:
    14 October 2019

Extended Research Article

Robotic-assisted surgery compared with laparoscopic resection surgery for rectal cancer: the ROLARR RCT

David Jayne
,
Alessio Pigazzi
,
Helen Marshall
,
Julie Croft
,
Neil Corrigan
,
Joanne Copeland
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 10
  • Published:
    26 September 2019

Extended Research Article

Oral morphine analgesia for preventing pain during invasive procedures in non-ventilated premature infants in hospital: the Poppi RCT

Vaneesha Monk
,
Fiona Moultrie
,
Caroline Hartley
,
Amy Hoskin
,
Gabrielle Green
,
Jennifer L Bell
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 9
  • Published:
    4 September 2019

Extended Research Article

Very low-dose dexamethasone to facilitate extubation of preterm babies at risk of bronchopulmonary dysplasia: the MINIDEX feasibility RCT

Helen Yates
,
Virginia Chiocchia
,
Louise Linsell
,
Nicolas Orsi
,
Edmund Juszczak
,
Kathryn Johnson
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 8
  • Published:
    2 September 2019

Extended Research Article

Minocycline for negative symptoms of schizophrenia and possible mechanistic actions: the BeneMin RCT

Bill Deakin
,
John Suckling
,
Paola Dazzan
,
Eileen Joyce
,
Stephen M Lawrie
,
Rachel Upthegrove
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 7
  • Published:
    29 August 2019

Extended Research Article

Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT

Sudeep Pushpakom
,
Ruwanthi Kolamunnage-Dona
,
Claire Taylor
,
Terry Foster
,
Catherine Spowart
,
Marta Garcia-Finana
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 6
  • Published:
    18 July 2019

Extended Research Article

Dopamine Augmented Rehabilitation in Stroke (DARS): a multicentre double-blind, randomised controlled trial of co-careldopa compared with placebo, in addition to routine NHS occupational and physical therapy, delivered early after stroke on functional recovery

Gary A Ford
,
Bipin B Bhakta
,
Alastair Cozens
,
Bonnie Cundill
,
Suzanne Hartley
,
Ivana Holloway
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 5
  • Published:
    10 July 2019

Extended Research Article

Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT

Mark A Hull
,
Kirsty Sprange
,
Trish Hepburn
,
Wei Tan
,
Aisha Shafayat
,
Colin J Rees
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 4
  • Published:
    3 July 2019

Extended Research Article

Developing and applying a framework to understand mechanisms of action in group-based, behaviour change interventions: the MAGI mixed-methods study

Aleksandra J Borek
,
Jane R Smith
,
Colin J Greaves
,
Fiona Gillison
,
Mark Tarrant
,
Sarah Morgan-Trimmer
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 3
  • Published:
    24 June 2019

Extended Research Article

Lightmasks that prevent dark adaptation for non-central diabetic macular oedema: the CLEOPATRA RCT

Sobha Sivaprasad
,
Joana Vasconcelos
,
Helen Holmes
,
Caroline Murphy
,
Joanna Kelly
,
Philip Hykin
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 2
  • Published:
    4 March 2019

Extended Research Article

Sperm selection for assisted reproduction by prior hyaluronan binding: the HABSelect RCT

Jackson Kirkman-Brown
,
Sue Pavitt
,
Yacoub Khalaf
,
Sheena Lewis
,
Richard Hooper
,
Siladitya Bhattacharya
et al.
  • Journal:
    Efficacy and Mechanism Evaluation Volume: 6, Issue: 1
  • Published:
    13 February 2019