Health Technology Assessment

Volume 15 (2011)

55 issues

Extended Research Article

A 1-year follow-on study from a randomised, head-to-head, multicentre, open-label study of two pandemic influenza vaccines in children

P de Whalley
,
W Walker
,
MD Snape
,
C Oeser
,
M Casey
,
P Moulsdale
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 45
  • Published:
    19 January 2012

Extended Research Article

The clinical effectiveness and cost-effectiveness of exercise referral schemes: a systematic review and economic evaluation

TG Pavey
,
N Anokye
,
AH Taylor
,
P Trueman
,
T Moxham
,
KR Fox
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 44
  • Published:
    20 December 2011

Extended Research Article

Evaluating meta-ethnography: systematic analysis and synthesis of qualitative research

R Campbell
,
P Pound
,
M Morgan
,
G Daker-White
,
N Britten
,
R Pill
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 43
  • Published:
    19 December 2011

Extended Research Article

Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis

N Fleeman
,
A Bagust
,
A Boland
,
R Dickson
,
Y Dundar
,
M Moonan
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 42
  • Published:
    12 December 2011

Extended Research Article

The clinical effectiveness and cost-effectiveness of bortezomib and thalidomide in combination regimens with an alkylating agent and a corticosteroid for the first-line treatment of multiple myeloma: a systematic review and economic evaluation

J Picot
,
K Cooper
,
J Bryant
,
AJ Clegg
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 41
  • Published:
    12 December 2011

Extended Research Article

A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease

H Squires
,
E Simpson
,
Y Meng
,
S Harnan
,
JW Stevens
,
R Wong
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 40
  • Published:
    12 December 2011

Extended Research Article

The clinical effectiveness and costeffectiveness of management strategies for sciatica: systematic review and economic model

R Lewis
,
N Williams
,
HE Matar
,
N Din
,
D Fitzsimmons
,
C Phillips
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 39
  • Published:
    15 November 2011

Extended Research Article

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease: a systematic review

D Shyangdan
,
C Clar
,
N Ghouri
,
R Henderson
,
T Gurung
,
D Preiss
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 38
  • Published:
    14 November 2011

Extended Research Article

Adaptive e-learning to improve dietary behaviour: a systematic review and cost-effectiveness analysis

J Harris
,
L Felix
,
A Miners
,
E Murray
,
S Michie
,
E Ferguson
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 37
  • Published:
    31 October 2011

Extended Research Article

Hemiarthroplasty and total hip arthroplasty for treating primary intracapsular fracture of the hip: a systematic review and cost-effectiveness analysis

C Carroll
,
M Stevenson
,
A Scope
,
P Evans
,
S Buckley
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 36
  • Published:
    10 October 2011

Extended Research Article

The value of FDG positron emission tomography/ computerised tomography (PET/CT) in pre-operative staging of colorectal cancer: a systematic review and economic evaluation

J Brush
,
K Boyd
,
F Chappell
,
F Crawford
,
M Dozier
,
E Fenwick
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 35
  • Published:
    11 October 2011

Extended Research Article

The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews, registry database analyses and economic evaluation

C Robertson
,
SK Arcot Ragupathy
,
C Boachie
,
JM Dixon
,
C Fraser
,
R Hernández
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 34
  • Published:
    27 September 2011

Extended Research Article

The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review

N Fleeman
,
C Martin Saborido
,
K Payne
,
A Boland
,
R Dickson
,
Y Dundar
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 33
  • Published:
    19 September 2011

Extended Research Article

EVerT: cryotherapy versus salicylic acid for the treatment of verrucae - a randomised controlled trial

S Cockayne
,
M Curran
,
G Denby
,
F Hashmi
,
C Hewitt
,
K Hicks
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 32
  • Published:
    19 September 2011

Extended Research Article

Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis

J Greenhalgh
,
A Bagust
,
A Boland
,
C Martin Saborido
,
J Oyee
,
M Blundell
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 31
  • Published:
    12 September 2011

Extended Research Article

Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection

C Gibbons
,
J Bruce
,
J Carpenter
,
AP Wilson
,
J Wilson
,
A Pearson
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 30
  • Published:
    12 September 2011

Extended Research Article

Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: the DEPICTED study

JW Gregory
,
M Robling
,
K Bennert
,
S Channon
,
D Cohen
,
E Crowne
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 29
  • Published:
    22 August 2011

Extended Research Article

A study of the safety and harms of antidepressant drugs for older people: a cohort study using a large primary care database

CAC Coupland
,
P Dhiman
,
G Barton
,
R Morriss
,
A Arthur
,
T Sach
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 28
  • Published:
    2 August 2011

Extended Research Article

Diagnostic management strategies for adults and children with minor head injury: a systematic review and an economic evaluation

A Pandor
,
S Goodacre
,
S Harnan
,
M Holmes
,
A Pickering
,
P Fitzgerald
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 27
  • Published:
    2 August 2011

Extended Research Article

Bone-anchored hearing aids (BAHAs) for people who are bilaterally deaf: a systematic review and economic evaluation

JL Colquitt
,
J Jones
,
P Harris
,
E Loveman
,
A Bird
,
AJ Clegg
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 26
  • Published:
    12 July 2011

Extended Research Article

Clinical effectiveness and cost-effectiveness of imatinib dose escalation for the treatment of unresectable and/or metastatic gastrointestinal stromal tumours that have progressed on treatment at a dose of 400 mg/day: a systematic review and economic evaluation

J Hislop
,
Z Quayyum
,
A Elders
,
C Fraser
,
D Jenkinson
,
G Mowatt
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 25
  • Published:
    27 June 2011

Extended Research Article

Conservative treatment for urinary incontinence in Men After Prostate Surgery (MAPS): two parallel randomised controlled trials

C Glazener
,
C Boachie
,
B Buckley
,
C Cochran
,
G Dorey
,
A Grant
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 24
  • Published:
    9 June 2011

Extended Research Article

The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department

S Goodacre
,
M Bradburn
,
P Fitzgerald
,
E Cross
,
P Collinson
,
A Gray
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 23
  • Published:
    31 May 2011

Extended Research Article

Evidence Review Group approaches to the critical appraisal of manufacturer submissions for the NICE STA process: a mapping study and thematic analysis

E Kaltenthaler
,
A Boland
,
C Carroll
,
R Dickson
,
P Fitzgerald
,
D Papaioannou
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 22
  • Published:
    13 May 2011

Extended Research Article

A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study)

D Price
,
S Musgrave
,
E Wilson
,
E Sims
,
L Shepstone
,
A Blyth
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 21
  • Published:
    10 May 2011

Extended Research Article

Evaluation of patient reporting of adverse drug reactions to the UK 'Yellow Card Scheme': literature review, descriptive and qualitative analyses, and questionnaire surveys

AJ Avery
,
C Anderson
,
CM Bond
,
H Fortnum
,
A Gifford
,
PC Hannaford
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 20
  • Published:
    13 May 2011

Extended Research Article

Hysterectomy, endometrial ablation and Mirena® for heavy menstrual bleeding: a systematic review of clinical effectiveness and costeffectiveness analysis

S Bhattacharya
,
LJ Middleton
,
A Tsourapas
,
AJ Lee
,
R Champaneria
,
JP Daniels
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 19
  • Published:
    3 May 2011

Extended Research Article

An economic evaluation of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence

P Auguste
,
P Barton
,
C Hyde
,
TE Roberts
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 18
  • Published:
    3 May 2011

Extended Research Article

Peginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV co-infection: a systematic review and economic evaluation

D Hartwell
,
J Jones
,
L Baxter
,
J Shepherd
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 17
  • Published:
    11 April 2011

Extended Research Article

The clinical effectiveness and safety of prophylactic retinal interventions to reduce the risk of retinal detachment and subsequent vision loss in adults and children with Stickler syndrome: a systematic review

C Carroll
,
D Papaioannou
,
A Rees
,
E Kaltenthaler
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 16
  • Published:
    11 April 2011

Extended Research Article

Processes in recruitment to randomised controlled trials of medicines for children (RECRUIT): a qualitative study

V Shilling
,
PR Williamson
,
H Hickey
,
E Sowden
,
RL Smyth
,
B Young
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 15
  • Published:
    4 April 2011

Extended Research Article

Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a tumour necrosis factor inhibitor: a systematic review and economic evaluation

K Malottki
,
P Barton
,
A Tsourapas
,
AO Uthman
,
Z Liu
,
K Routh
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 14
  • Published:
    4 April 2011

Extended Research Article

VenUS III: a randomised controlled trial of therapeutic ultrasound in the management of venous leg ulcers

JM Watson
,
AR Kang’ombe
,
MO Soares
,
L-H Chuang
,
G Worthy
,
JM Bland
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 13
  • Published:
    7 March 2011

Extended Research Article

A randomised controlled trial of post-operative radiotherapy following breast-conserving surgery in a minimum-risk population. Quality of life at 5 years in the PRIME trial

LJ Williams
,
IH Kunkler
,
CC King
,
W Jack
,
M van der Pol
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 12
  • Published:
    3 March 2011

Extended Research Article

Growth monitoring for short stature: update of a systematic review and economic model

D Craig
,
D Fayter
,
L Stirk
,
R Crott
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 11
  • Published:
    3 March 2011

Extended Research Article

Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis: a systematic review and economic evaluation

M Rodgers
,
D Epstein
,
L Bojke
,
H Yang
,
D Craig
,
T Fonseca
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 10
  • Published:
    15 February 2011

Extended Research Article

An evidence synthesis of qualitative and quantitative research on component intervention techniques, effectiveness, cost-effectiveness, equity and acceptability of different versions of health-related lifestyle advisor role in improving health

SM Carr
,
M Lhussier
,
N Forster
,
L Geddes
,
K Deane
,
M Pennington
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 9
  • Published:
    11 February 2011

Extended Research Article

A multicentre randomised controlled trial and economic evaluation of ion-exchange water softeners for the treatment of eczema in children: the Softened Water Eczema Trial (SWET)

KS Thomas
,
K Koller
,
T Dean
,
CJ O’Leary
,
TH Sach
,
A Frost
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 8
  • Published:
    11 February 2011

Extended Research Article

Accuracy of bacterial DNA testing for central venous catheter-associated bloodstream infection in children with cancer

M Millar
,
W Zhou
,
R Skinner
,
B Pizer
,
E Hennessy
,
M Wilks
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 7
  • Published:
    11 February 2011

Extended Research Article

A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-a) inhibitors, adalimumab and infliximab, for Crohn's disease

J Dretzke
,
R Edlin
,
J Round
,
M Connock
,
C Hulme
,
J Czeczot
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 6
  • Published:
    11 February 2011

Extended Research Article

Palivizumab for immunoprophylaxis of respiratory syncytial virus (RSV) bronchiolitis in high-risk infants and young children: systematic review and additional economic modelling of subgroup analyses

D Wang
,
S Bayliss
,
C Meads
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 5
  • Published:
    31 January 2011

Extended Research Article

Positron emission tomography (PET) and magnetic resonance imaging (MRI) for the assessment of axillary lymph node metastases in early breast cancer: systematic review and economic evaluation

KL Cooper
,
Y Meng
,
S Harnan
,
SE Ward
,
P Fitzgerald
,
D Papaioannou
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 4
  • Published:
    31 January 2011

Extended Research Article

MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial

HC Kitchener
,
R Blanks
,
H Cubie
,
M Desai
,
G Dunn
,
R Legood
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 3
  • Published:
    31 January 2011

Extended Research Article

The clinical effectiveness and cost-effectiveness of long-term weight management schemes for adults: a systematic review

E Loveman
,
GK Frampton
,
J Shepherd
,
J Picot
,
K Cooper
,
J Bryant
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 2
  • Published:
    28 January 2011

Extended Research Article

Assessing the surgical skills of trainees in the operating theatre: a prospective observational study of the methodology

JD Beard
,
J Marriott
,
H Purdie
,
J Crossley
  • Journal:
    Health Technology Assessment Volume: 15, Issue: 1
  • Published:
    28 January 2011

Extended Research Article

Bevacizumab in combination with a taxane for the first-line treatment of HER2-negative metastatic breast cancer

M Rodgers
,
M Soares
,
D Epstein
,
H Yang
,
D Fox
,
A Eastwood
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 1
  • Published:
    14 June 2011

Extended Research Article

Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years

S Walker
,
J Burch
,
C McKenna
,
K Wright
,
S Griffin
,
N Woolacott
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 2
  • Published:
    14 June 2011

Extended Research Article

Eltrombopag for the treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP)

D Boyers
,
X Jia
,
M Crowther
,
D Jenkinson
,
C Fraser
,
G Mowatt
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 3
  • Published:
    14 June 2011

Extended Research Article

Trastuzumab for the treatment of HER2 positive metastatic adenocarcinoma of the stomach or gastro-oesophageal junction

G Norman
,
S Rice
,
E Spackman
,
L Stirk
,
A Danso-Appiah
,
D Suh
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 4
  • Published:
    14 June 2011

Extended Research Article

Prucalopride for the treatment of women with chronic constipation in whom standard laxative regimens have failed to provide adequate relief

M Pennant
,
R Orlando
,
P Barton
,
S Bayliss
,
K Routh
,
C Meads
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 5
  • Published:
    14 June 2011

Extended Research Article

Denosumab for the prevention of osteoporotic fractures in postmenopausal women

N Waugh
,
P Royle
,
G Scotland
,
R Henderson
,
R Hollick
,
P McNamee
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 6
  • Published:
    14 June 2011

Extended Research Article

Ofatumumab for the treatment of chronic lymphocytic leukaemia in patients who are refractory to fludarabine and alemtuzumab: a critique of the submission from GSK

M Hoyle
,
L Crathorne
,
R Garside
,
C Hyde
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 7
  • Published:
    14 June 2011

Extended Research Article

Trabectedin for the treatment of relapsed ovarian cancer

D Papaioannou
,
R Rafia
,
MD Stevenson
,
JW Stevens
,
P Evans
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 8
  • Published:
    14 June 2011

Extended Research Article

Liraglutide for the treatment of type 2 diabetes

D Shyangdan
,
E Cummins
,
P Royle
,
N Waugh
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 9
  • Published:
    14 June 2011

Extended Research Article

Golimumab for the treatment of psoriatic arthritis

H Yang
,
D Epstein
,
L Bojke
,
D Craig
,
K Light
,
I Bruce
et al.
  • Journal:
    Health Technology Assessment Volume: 15, Issue: Suppl 1 Article 10
  • Published:
    14 June 2011