Health Technology Assessment

Volume 26 (2022)

51 issues

Extended Research Article

Oral nutritional interventions in frail older people who are malnourished or at risk of malnutrition: a systematic review

Katie Thomson
,
Stephen Rice
,
Oluwatomi Arisa
,
Eugenie Johnson
,
Louise Tanner
,
Christopher Marshall
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 51
  • Published:
    21 December 2022

Extended Research Article

Standard threshold laser versus subthreshold micropulse laser for adults with diabetic macular oedema: the DIAMONDS non-inferiority RCT

Noemi Lois
,
Christina Campbell
,
Norman Waugh
,
Augusto Azuara-Blanco
,
Mandy Maredza
,
Hema Mistry
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 50
  • Published:
    21 December 2022

Extended Research Article

EarlyCDT Lung blood test for risk classification of solid pulmonary nodules: systematic review and economic evaluation

Ana Duarte
,
Mark Corbett
,
Hollie Melton
,
Melissa Harden
,
Stephen Palmer
,
Marta Soares
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 49
  • Published:
    19 December 2022

Extended Research Article

Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT

Eric Lim
,
Rosie A Harris
,
Holly E McKeon
,
Timothy JP Batchelor
,
Joel Dunning
,
Michael Shackcloth
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 48
  • Published:
    16 December 2022

Extended Research Article

Single-incision mini-slings versus standard synthetic mid-urethral slings for surgical treatment of stress urinary incontinence in women: The SIMS RCT

Mohamed Abdel-Fattah
,
David Cooper
,
Tracey Davidson
,
Mary Kilonzo
,
Dwayne Boyers
,
Kiron Bhal
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 47
  • Published:
    15 December 2022

Extended Research Article

Photobiomodulation in the management of oral mucositis for adult head and neck cancer patients receiving irradiation: the LiTEFORM RCT

Michael Nugent
,
Valerie Bryant
,
Chrissie Butcher
,
Holly Fisher
,
Sean Gill
,
Rebecca Goranova
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 46
  • Published:
    9 December 2022

Extended Research Article

SeHCAT (tauroselcholic [75selenium] acid) for the investigation of bile acid diarrhoea in adults: a systematic review and cost-effectiveness analysis

Marie Westwood
,
Isaac Corro Ramos
,
Nigel Armstrong
,
Edyta Ryczek
,
Hannah Penton
,
Marscha Holleman
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 45
  • Published:
    22 November 2022

Extended Research Article

Defining the optimum strategy for identifying adults and children with coeliac disease: systematic review and economic modelling

Martha MC Elwenspoek
,
Howard Thom
,
Athena L Sheppard
,
Edna Keeney
,
Rachel O’Donnell
,
Joni Jackson
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 44
  • Published:
    1 November 2022

Extended Research Article

Assessing a 12-month course of oral alendronate for adults with avascular necrosis of the hip: MANTIS RCT with internal pilot

Sion Glyn-Jones
,
Muhammad K Javaid
,
David Beard
,
Julia Newton
,
Robert Kerslake
,
Callum McBryde
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 43
  • Published:
    1 November 2022

Extended Research Article

One-session treatment compared with multisession CBT in children aged 7 16 years with specific phobias: the ASPECT non-inferiority RCT

Barry Wright
,
Lucy Tindall
,
Alexander J Scott
,
Ellen Lee
,
Katie Biggs
,
Cindy Cooper
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 42
  • Published:
    1 November 2022

Extended Research Article

Patient preferences and current practice for adults with steroid-resistant ulcerative colitis: POPSTER mixed-methods study

Elizabeth Coates
,
Nyantara Wickramasekera
,
Amy Barr
,
Phil Shackley
,
Matthew Lee
,
Daniel Hind
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 41
  • Published:
    28 October 2022

Extended Research Article

Photodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT

Rakesh Heer
,
Rebecca Lewis
,
Anne Duncan
,
Steven Penegar
,
Thenmalar Vadiveloo
,
Emma Clark
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 40
  • Published:
    27 October 2022

Extended Research Article

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Solomon Tesfaye
,
Gordon Sloan
,
Jennifer Petrie
,
David White
,
Mike Bradburn
,
Tracey Young
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 39
  • Published:
    19 October 2022

Extended Research Article

Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT

David Jayne
,
Michael Walsh
,
Peter A Merkel
,
Chen Au Peh
,
Wladimir Szpirt
,
Xavier Puéchal
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 38
  • Published:
    26 September 2022

Extended Research Article

Early computed tomography coronary angiography in adults presenting with suspected acute coronary syndrome: the RAPID-CTCA RCT

Alasdair J Gray
,
Carl Roobottom
,
Jason E Smith
,
Steve Goodacre
,
Katherine Oatey
,
Rachel O’Brien
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 37
  • Published:
    5 September 2022

Extended Research Article

Synthetic sling or artificial urinary sphincter for men with urodynamic stress incontinence after prostate surgery: the MASTER non-inferiority RCT

Lynda Constable
,
Paul Abrams
,
David Cooper
,
Mary Kilonzo
,
Nikki Cotterill
,
Chris Harding
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 36
  • Published:
    15 August 2022

Extended Research Article

A modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT

Paula Oliveira
,
Eloise Stevens
,
Lydia Barge
,
Julie Comyn
,
Kirsty Langley
,
Paul Ramchandani
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 35
  • Published:
    12 August 2022

Extended Research Article

Hughes abdominal closure versus standard mass closure to reduce incisional hernias following surgery for colorectal cancer: the HART RCT

Susan O’Connell
,
Saiful Islam
,
Bernadette Sewell
,
Angela Farr
,
Laura Knight
,
Nadim Bashir
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 34
  • Published:
    8 August 2022

Extended Research Article

Offer of a bandage versus rigid immobilisation in 4- to 15-year-olds with distal radius torus fractures: the FORCE equivalence RCT

Daniel C Perry
,
Juul Achten
,
Ruth Knight
,
Susan J Dutton
,
Melina Dritsaki
,
James M Mason
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 33
  • Published:
    29 July 2022

Extended Research Article

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis

Joanne Reeve
,
Michelle Maden
,
Ruaraidh Hill
,
Amadea Turk
,
Kamal Mahtani
,
Geoff Wong
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 32
  • Published:
    27 July 2022

Extended Research Article

Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT

Caroline Watkins
,
Svetlana Tishkovskaya
,
Chris Brown
,
Chris Sutton
,
Yvonne Sylvestre Garcia
,
Denise Forshaw
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 31
  • Published:
    26 July 2022

Extended Research Article

Long-term impact of pre-incision antibiotics on children born by caesarean section: a longitudinal study based on UK electronic health records

Dana Šumilo
,
Krishnarajah Nirantharakumar
,
Brian H Willis
,
Gavin M Rudge
,
James Martin
,
Krishna Gokhale
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 30
  • Published:
    1 July 2022

Extended Research Article

Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT

Elizabeth Randell
,
Melissa Wright
,
Sarah Milosevic
,
David Gillespie
,
Lucy Brookes-Howell
,
Monica Busse-Morris
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 29
  • Published:
    29 June 2022

Extended Research Article

Infective endocarditis following invasive dental procedures: IDEA case-crossover study

Martin H Thornhill
,
Annabel Crum
,
Saleema Rex
,
Richard Campbell
,
Tony Stone
,
Mike Bradburn
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 28
  • Published:
    1 June 2022

Extended Research Article

Digital smartphone intervention to recognise and manage early warning signs in schizophrenia to prevent relapse: the EMPOWER feasibility cluster RCT

Andrew I Gumley
,
Simon Bradstreet
,
John Ainsworth
,
Stephanie Allan
,
Mario Alvarez-Jimenez
,
Maximillian Birchwood
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 27
  • Published:
    31 May 2022

Extended Research Article

Colonoscopy surveillance following adenoma removal to reduce the risk of colorectal cancer: a retrospective cohort study

Amanda J Cross
,
Emma C Robbins
,
Kevin Pack
,
Iain Stenson
,
Paula L Kirby
,
Bhavita Patel
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 26
  • Published:
    30 May 2022

Extended Research Article

Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT

Abha Maheshwari
,
Vasha Bari
,
Jennifer L Bell
,
Siladitya Bhattacharya
,
Priya Bhide
,
Ursula Bowler
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 25
  • Published:
    23 May 2022

Extended Research Article

An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia: the Journeying through Dementia RCT

Gail Mountain
,
Jessica Wright
,
Cindy L Cooper
,
Ellen Lee
,
Kirsty Sprange
,
Jules Beresford-Dent
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 24
  • Published:
    10 May 2022

Extended Research Article

Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT

Chris Harding
,
Thomas Chadwick
,
Tara Homer
,
Jan Lecouturier
,
Helen Mossop
,
Sonya Carnell
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 23
  • Published:
    10 May 2022

Extended Research Article

Uterine artery embolisation versus myomectomy for premenopausal women with uterine fibroids wishing to avoid hysterectomy: the FEMME RCT

Jane Daniels
,
Lee J Middleton
,
Versha Cheed
,
William McKinnon
,
Dikshyanta Rana
,
Fusun Sirkeci
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 22
  • Published:
    12 April 2022

Extended Research Article

Supraglottic airway device versus tracheal intubation in the initial airway management of out-of-hospital cardiac arrest: the AIRWAYS-2 cluster RCT

Jonathan R Benger
,
Kim Kirby
,
Sarah Black
,
Stephen J Brett
,
Madeleine Clout
,
Michelle J Lazaroo
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 21
  • Published:
    11 April 2022

Extended Research Article

Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis

Moira Cruickshank
,
Mari Imamura
,
Corinne Booth
,
Lorna Aucott
,
Carl Counsell
,
Paul Manson
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 20
  • Published:
    23 March 2022

Extended Research Article

Shockwave lithotripsy compared with ureteroscopic stone treatment for adults with ureteric stones: the TISU non-inferiority RCT

Ranan Dasgupta
,
Sarah Cameron
,
Lorna Aucott
,
Graeme MacLennan
,
Mary M Kilonzo
,
Thomas BL Lam
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 19
  • Published:
    17 March 2022

Extended Research Article

Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT

Bronagh Blackwood
,
Kevin P Morris
,
Joanne Jordan
,
Lisa McIlmurray
,
Ashley Agus
,
Roisin Boyle
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 18
  • Published:
    15 March 2022

Extended Research Article

Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling

Fiona J Gilbert
,
Scott Harris
,
Kenneth A Miles
,
Jonathan R Weir-McCall
,
Nagmi R Qureshi
,
Robert C Rintoul
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 17
  • Published:
    15 March 2022

Extended Research Article

Arthroscopic hip surgery compared with personalised hip therapy in people over 16 years old with femoroacetabular impingement syndrome: UK FASHIoN RCT

Damian R Griffin
,
Edward J Dickenson
,
Felix Achana
,
James Griffin
,
Joanna Smith
,
Peter DH Wall
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 16
  • Published:
    1 March 2022

Extended Research Article

Exercise to prevent shoulder problems after breast cancer surgery: the PROSPER RCT

Julie Bruce
,
Bruno Mazuquin
,
Pankaj Mistry
,
Sophie Rees
,
Alastair Canaway
,
Anower Hossain
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 15
  • Published:
    28 February 2022

Extended Research Article

A peer-delivered intervention to reduce harm and improve the well-being of homeless people with problem substance use: the SHARPS feasibility mixed-methods study

Tessa Parkes
,
Catriona Matheson
,
Hannah Carver
,
Rebecca Foster
,
John Budd
,
Dave Liddell
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 14
  • Published:
    25 February 2022

Extended Research Article

Heparin versus citrate anticoagulation for continuous renal replacement therapy in intensive care: the RRAM observational study

Doug W Gould
,
James Doidge
,
M Zia Sadique
,
Mark Borthwick
,
Robert Hatch
,
Fergus J Caskey
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 13
  • Published:
    24 February 2022

Extended Research Article

A rapid intrapartum test for group B Streptococcus to reduce antibiotic usage in mothers with risk factors: the GBS2 cluster RCT

Jane Daniels
,
Emily F Dixon
,
Alicia Gill
,
Jon Bishop
,
Maria D’Amico
,
Khaled Ahmed
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 12
  • Published:
    23 February 2022

Extended Research Article

Moulded cast compared with K-wire fixation after manipulation of an acute dorsally displaced distal radius fracture: the DRAFFT 2 RCT

Matthew L Costa
,
Juul Achten
,
Alexander Ooms
,
May Ee Png
,
Jonathan Cook
,
Melina Dritsaki
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 11
  • Published:
    11 February 2022

Extended Research Article

Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review

Mostafa Metwally
,
Robin Chatters
,
Clare Pye
,
Munya Dimairo
,
David White
,
Stephen Walters
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 10
  • Published:
    2 February 2022

Extended Research Article

A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT

Philippa A Logan
,
Jane C Horne
,
Frances Allen
,
Sarah J Armstrong
,
Allan B Clark
,
Simon Conroy
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 9
  • Published:
    2 February 2022

Extended Research Article

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

Katie Banister
,
Jonathan A Cook
,
Graham Scotland
,
Augusto Azuara-Blanco
,
Beatriz Goulão
,
Heinrich Heimann
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 8
  • Published:
    2 February 2022

Extended Research Article

Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis

Miriam Brazzelli
,
Lorna Aucott
,
Magaly Aceves-Martins
,
Clare Robertson
,
Elisabet Jacobsen
,
Mari Imamura
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 7
  • Published:
    2 February 2022

Extended Research Article

Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study

Linda Sharples
,
Priya Sastry
,
Carol Freeman
,
Joanne Gray
,
Andrew McCarthy
,
Yi-Da Chiu
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 6
  • Published:
    26 January 2022

Extended Research Article

Shock-absorbing flooring for fall-related injury prevention in older adults and staff in hospitals and care homes: the SAFEST systematic review

Amy Drahota
,
Lambert M Felix
,
James Raftery
,
Bethany E Keenan
,
Chantelle C Lachance
,
Dawn C Mackey
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 5
  • Published:
    25 January 2022

Extended Research Article

Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation

Lindsay Claxton
,
Mark Simmonds
,
Lucy Beresford
,
Richard Cubbon
,
Mark Dayer
,
Stephen S Gottlieb
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 4
  • Published:
    24 January 2022

Extended Research Article

Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection: PREDNOS2 RCT

Martin T Christian
,
Nicholas JA Webb
,
Rebecca L Woolley
,
Nafsika Afentou
,
Samir Mehta
,
Emma Frew
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 3
  • Published:
    19 January 2022

Extended Research Article

Lactic acid gel versus metronidazole for recurrent bacterial vaginosis in women aged 16 years and over: the VITA RCT

Lindsay Armstrong-Buisseret
,
Clare Brittain
,
Joe Kai
,
Miruna David
,
Jocelyn Anstey Watkins
,
Mara Ozolins
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 2
  • Published:
    18 January 2022

Extended Research Article

Digital interventions in mental health: evidence syntheses and economic modelling

Lina Gega
,
Dina Jankovic
,
Pedro Saramago
,
David Marshall
,
Sarah Dawson
,
Sally Brabyn
et al.
  • Journal:
    Health Technology Assessment Volume: 26, Issue: 1
  • Published:
    18 January 2022