Volume 18 (2014)

Prospective multi-centre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children. The SLEEPS Study (Safety ProfiLe, Efficacy and Equivalence in Paediatric intensive care Sedation)

• Journal:
  Health Technology Assessment Volume: 18, Issue: 71
• Published:
  24 December 2014

The use of fenestrated and branched endovascular aneurysm repair (fEVAR & bEVAR) for juxta-renal and thoraco-abdominal aneurysms: a systematic review and cost effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 70
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  22 December 2014

Optical coherence tomography for the diagnosis, monitoring, and guiding of treatment for neovascular age-related macular degeneration: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 69
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  27 November 2014

The clinical and cost-effectiveness of second-eye cataract surgery: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 68
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  18 November 2014

Clinical and cost-effectiveness results from the TOMADO randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea-hypopnoea and long-term economic analysis of oral devices and continuous positive airway pressure

• Journal:
  Health Technology Assessment Volume: 18, Issue: 67
• Published:
  3 November 2014

Randomised controlled trial of tumour-necrosis-factor inhibitors against combination intensive therapy with conventional disease modifying anti-rheumatic drugs in established rheumatoid arthritis: The TACIT trial and associated systematic reviews

• Journal:
  Health Technology Assessment Volume: 18, Issue: 66
• Published:
  29 October 2014

The clinical effectiveness and cost-effectiveness of peginterferon alfa and ribavirin for the treatment of chronic hepatitis C in children and young people: a systematic review and economic evaluation

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  Health Technology Assessment Volume: 18, Issue: 65
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  29 October 2014

Assessing the risk of self-harm in an adult offender population

• Journal:
  Health Technology Assessment Volume: 18, Issue: 64
• Published:
  28 October 2014

Probiotics for Antibiotic-Associated Diarrhoea (PAAD): a prospective observational study of antibiotic-associated diarrhoea (including Clostridium difficile-associated diarrhoea) in care homes

• Journal:
  Health Technology Assessment Volume: 18, Issue: 63
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  22 October 2014

KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 62
• Published:
  15 October 2014

START (STrAtegies for RelaTives) study: a pragmatic randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of a manual-based coping strategy programme in promoting the mental health of carers of people with dementia

• Journal:
  Health Technology Assessment Volume: 18, Issue: 61
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  9 October 2014

Assessment of the feasibility and clinical value of further research to evaluate the management options for children with Down syndrome and otitis media

• Journal:
  Health Technology Assessment Volume: 18, Issue: 60
• Published:
  1 October 2014

Systematic review and modelling of the cost effectiveness of Cardiac Magnetic Resonance Imaging compared to current existing testing pathways in Ischaemic Cardiomyopathy

• Journal:
  Health Technology Assessment Volume: 18, Issue: 59
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  29 September 2014

A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome

• Journal:
  Health Technology Assessment Volume: 18, Issue: 58
• Published:
  22 September 2014

VenUS IV (Venous leg Ulcer Study IV): Compression hosiery versus compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed treatment comparison and decision analytic model.

• Journal:
  Health Technology Assessment Volume: 18, Issue: 57
• Published:
  22 September 2014

Implantable cardioverter defibrillators for the treatment of arrhythmias and cardiac resynchronisation therapy for the treatment of heart failure: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 56
• Published:
  1 September 2014

Clinical and cost-effectiveness of cholecystectomy versus observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 55
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  1 September 2014

The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy; effectiveness and safety until 2 years after delivery, with economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 54
• Published:
  26 August 2014

Can rapid integrated Polymerase Chain Reaction (PCR)-based diagnostics for Gastrointestinal pathogens improve routine hospital infection control practice? A diagnostic study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 53
• Published:
  26 August 2014

The effectiveness of collaborative care for people with memory problems in primary care: results of the CAREDEM case management modelling and feasibility study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 52
• Published:
  20 August 2014

Systematic review to identify and appraise outcome measures used to evaluate childhood obesity treatment interventions: evidence of purpose, application, validity, reliability and sensitivity

• Journal:
  Health Technology Assessment Volume: 18, Issue: 51
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  18 August 2014

Clinical effectiveness of interventions for treatment-resistant anxiety in older people; a systematic review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 50
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  12 August 2014

Multi-centre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care

• Journal:
  Health Technology Assessment Volume: 18, Issue: 49
• Published:
  7 August 2014

Folate Augmentation of Treatment - Evaluation for Depression (FolATED): randomised trial and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 48
• Published:
  23 July 2014

Changing eating behaviours to treat childhood obesity in the community using mandolean: The community mandolean randomised trial (COMMANDO), A pilot study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 47
• Published:
  21 July 2014

Interventions for adult Eustachian tube dysfunction: A systematic review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 46
• Published:
  21 July 2014

Vitamin D supplementation in pregnancy: A systematic review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 45
• Published:
  15 July 2014

Coronary artery bypass grafting in High RISk patients randomised to Off Pump or On Pump Surgery - the CRISP trial

• Journal:
  Health Technology Assessment Volume: 18, Issue: 44
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  15 July 2014

The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: evaluations of two exemplar trials

• Journal:
  Health Technology Assessment Volume: 18, Issue: 43
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  11 July 2014

Death, Bereavement and randomised controlled trials (BRACELET): a methodological study of policy and practice in neonatal and paediatric intensive care trials

• Journal:
  Health Technology Assessment Volume: 18, Issue: 42
• Published:
  2 July 2014

United Kingdom Oscillation Study: long-term outcomes of a randomised trial of two modes of neonatal ventilation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 41
• Published:
  30 June 2014

Allopurinol for chronic kidney disease: a systematic review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 40
• Published:
  26 June 2014

A systematic review of the effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia

• Journal:
  Health Technology Assessment Volume: 18, Issue: 39
• Published:
  23 June 2014

Maximising the value of combining qualitative research and randomised controlled trials in health research: the QUAlitative Research in Trials (QUART) study a mixed methods study.

• Journal:
  Health Technology Assessment Volume: 18, Issue: 38
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  10 June 2014

European network for Health Technology Assessment Joint Action (EUnetHTA JA): a process evaluation performed by questionnaires and documentary analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 37
• Published:
  10 June 2014

Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and Streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year olds

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  Health Technology Assessment Volume: 18, Issue: 36
• Published:
  30 May 2014

Systematic reviews and integrated report on the quantitative, qualitative and economic evidence base for the management of obesity in men

• Journal:
  Health Technology Assessment Volume: 18, Issue: 35
• Published:
  27 May 2014

A systematic review, psychometric analysis and qualitative assessment of Generic Preference-Based Measures of Health in Mental Health Populations and the estimation of mapping functions from widely used specific measures

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  Health Technology Assessment Volume: 18, Issue: 34
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  27 May 2014

What is the clinical effectiveness and cost effectiveness of cytisine compared with varenicline for smoking cessation: a systematic review and economic evaluation?

• Journal:
  Health Technology Assessment Volume: 18, Issue: 33
• Published:
  19 May 2014

Epidermal growth factor receptor tyrosine kinase (EGFR-TK) mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer: a systematic review and cost-effectiveness analysis

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  Health Technology Assessment Volume: 18, Issue: 32
• Published:
  15 May 2014

Clinical and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: the CoBalT randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 18, Issue: 31
• Published:
  14 May 2014

The clinical and cost effectiveness of brief intervention for excessive alcohol consumption among people attending sexual health clinics: a randomised controlled trial (SHEAR)

• Journal:
  Health Technology Assessment Volume: 18, Issue: 30
• Published:
  14 May 2014

Rehabilitation aimed at improving outdoor mobility for people after stroke: a multi-centre randomised controlled study (the Getting out of the House Study)

• Journal:
  Health Technology Assessment Volume: 18, Issue: 29
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  13 May 2014

Assessing methods to specify the target difference for a randomised controlled trial - DELTA (Difference ELicitation in TriAls) review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 28
• Published:
  13 May 2014

An assessment of the cost effectiveness of magnetic resonance including diffusion-weighted imaging in patients with transient ischaemic attack and minor stroke. A systematic review, meta-analysis and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 27
• Published:
  1 May 2014

A clinical and economic evaluation of Control of Hyperglycaemia in Paediatric intensive care (CHiP): a randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 18, Issue: 26
• Published:
  30 April 2014

Selective decontamination of the digestive tract in critically ill patients treated in intensive care units: a mixed-methods feasibility study (the SuDDICU study)

• Journal:
  Health Technology Assessment Volume: 18, Issue: 25
• Published:
  29 April 2014

Cost-effectiveness of diagnostic strategies for the management of abnormal uterine bleeding (heavy menstrual bleeding and post-menopausal bleeding): a decision analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 24
• Published:
  28 April 2014

'The clinical effectiveness and cost-effectiveness of primary human papillomavirus cervical screening in England: extended follow-up of the ARTISTIC randomised trial cohort through three screening rounds

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  Health Technology Assessment Volume: 18, Issue: 23
• Published:
  28 April 2014

The 3Mg Trial: A randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma

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  Health Technology Assessment Volume: 18, Issue: 22
• Published:
  14 April 2014

AMIPROM (Amnioinfusion in preterm premature rupture of membranes) A randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes - pilot study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 21
• Published:
  9 April 2014

Structured, intensive education maximising engagement, motivation and long-term change for children and young people with diabetes: a cluster randomised controlled trial with integral process and economic evaluation the CASCADE study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 20
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  1 April 2014

A randomised controlled trial of the clinical effectiveness and cost-effectiveness of different knee prostheses: the Knee Arthroplasty Trial (KAT)

• Journal:
  Health Technology Assessment Volume: 18, Issue: 19
• Published:
  31 March 2014

Ivacaftor for the treatment of patients with cystic fibrosis and the G551D mutation: a systematic review and cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 18
• Published:
  24 March 2014

Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures: a systematic review and cost-effectiveness analysis

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  Health Technology Assessment Volume: 18, Issue: 17
• Published:
  20 March 2014

Routine echocardiography in the management of stroke and transient ischaemic attack: a systematic review and economic evaluation

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  Health Technology Assessment Volume: 18, Issue: 16
• Published:
  10 March 2014

Educational interventions for preventing vascular catheter bloodstream infections in critical care: evidence map, systematic review and economic evaluation

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  Health Technology Assessment Volume: 18, Issue: 15
• Published:
  8 March 2014

Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment systematic review and modelling of progression and cost-effectiveness

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  Health Technology Assessment Volume: 18, Issue: 14
• Published:
  3 March 2014

A randomised controlled trial and cost-effectiveness evaluation of "booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods

• Journal:
  Health Technology Assessment Volume: 18, Issue: 13
• Published:
  27 February 2014

Preparatory study for the revaluation of the EQ-5D tariff: methodology report

• Journal:
  Health Technology Assessment Volume: 18, Issue: 12
• Published:
  27 February 2014

Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups

• Journal:
  Health Technology Assessment Volume: 18, Issue: 11
• Published:
  18 February 2014

Enhancements to angioplasty for peripheral arterial occlusive disease (PAD): systematic review, cost-effectiveness assessment and expected value of information analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 10
• Published:
  17 February 2014

Use of generic and condition-specific measures of health related quality of life in NICE decision-making: systematic review, statistical modeling and survey

• Journal:
  Health Technology Assessment Volume: 18, Issue: 9
• Published:
  13 February 2014

The clinical effectiveness, cost-effectiveness and acceptability of community-based interventions aimed at improving or maintaining quality of life in children of parents with serious mental illness: a systematic review

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  Health Technology Assessment Volume: 18, Issue: 8
• Published:
  10 February 2014

The clinical and cost effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 18, Issue: 7
• Published:
  3 February 2014

PRImary Care Streptococcal Management Study (PRISM): in vitro study, diagnostic cohorts, and a pragmatic adaptive randomised controlled trial with nested qualitative study and cost-effectiveness study

• Journal:
  Health Technology Assessment Volume: 18, Issue: 6
• Published:
  28 January 2014

Adenoidectomy with or without grommets for children with otitis media: an individual patient data meta-analysis

• Journal:
  Health Technology Assessment Volume: 18, Issue: 5
• Published:
  20 January 2014

A pilot randomised trial to assess the methods and procedures for evaluating the clinical effectiveness and cost-effectiveness of Exercise Assisted Reduction then Stop (EARS) among disadvantaged smokers

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  Health Technology Assessment Volume: 18, Issue: 4
• Published:
  20 January 2014

The feasibility of using a parenting programme for the prevention of unintentional home injuries in the under-fives: a cluster randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 18, Issue: 3
• Published:
  16 January 2014

Effectiveness and cost-effectiveness of traditional and new partner notification technologies for curable sexually transmitted infections: observational study, systematic reviews and mathematical modelling

• Journal:
  Health Technology Assessment Volume: 18, Issue: 2
• Published:
  9 January 2014

The effectiveness of sexual health interventions for people with severe mental illness: a systematic review

• Journal:
  Health Technology Assessment Volume: 18, Issue: 1
• Published:
  9 January 2014