Volume 25 (2021)

Behavioural interventions to promote physical activity in a multiethnic population at high risk of diabetes: PROPELS three-arm RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 77
• Published:
  6 January 2022

Modelling approaches for histology-independent cancer drugs to inform NICE appraisals: a systematic review and decision-framework

• Journal:
  Health Technology Assessment Volume: 25, Issue: 76
• Published:
  5 January 2022

Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

• Journal:
  Health Technology Assessment Volume: 25, Issue: 75
• Published:
  17 December 2021

Cue-based versus scheduled feeding for preterm infants transitioning from tube to oral feeding: the Cubs mixed-methods feasibility study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 74
• Published:
  8 December 2021

Improving continence in children and young people with neurodisability: a systematic review and survey

• Journal:
  Health Technology Assessment Volume: 25, Issue: 73
• Published:
  2 December 2021

Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 72
• Published:
  2 December 2021

Pharmacological and non-pharmacological treatments and outcomes for new-onset atrial fibrillation in ICU patients: the CAFE scoping review and database analyses

• Journal:
  Health Technology Assessment Volume: 25, Issue: 71
• Published:
  30 November 2021

Social recovery therapy for young people with emerging severe mental illness: the Prodigy RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 70
• Published:
  29 November 2021

Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 69
• Published:
  29 November 2021

Mifepristone and misoprostol versus placebo and misoprostol for resolution of miscarriage in women diagnosed with missed miscarriage: the MifeMiso RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 68
• Published:
  25 November 2021

Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 67
• Published:
  24 November 2021

Unicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting

• Journal:
  Health Technology Assessment Volume: 25, Issue: 66
• Published:
  22 November 2021

Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and Pseudomonas aeruginosa infection: the TORPEDO-CF RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 65
• Published:
  22 November 2021

Optimal surveillance strategies for Patients with stage 1 cutaneous melanoma post primary tumour excision: three systematic reviews and an economic model

• Journal:
  Health Technology Assessment Volume: 25, Issue: 64
• Published:
  18 November 2021

Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 63
• Published:
  12 November 2021

Surgery versus conservative management of stable thoracolumbar fracture: the PRESTO feasibility RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 62
• Published:
  12 November 2021

Feasibility and design of a trial regarding the optimal mode of delivery for preterm birth: the CASSAVA multiple methods study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 61
• Published:
  9 November 2021

Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 60
• Published:
  4 November 2021

Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 25, Issue: 59
• Published:
  20 October 2021

A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 58
• Published:
  19 October 2021

Framework for the development and evaluation of complex interventions: gap analysis, workshop and consultation-informed update

• Journal:
  Health Technology Assessment Volume: 25, Issue: 57
• Published:
  30 September 2021

Non-invasive imaging software to assess the functional significance of coronary stenoses: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 25, Issue: 56
• Published:
  29 September 2021

Reducing bias in trials from reactions to measurement: the MERIT study including developmental work and expert workshop

• Journal:
  Health Technology Assessment Volume: 25, Issue: 55
• Published:
  22 September 2021

Acceptance and commitment therapy for older people with treatment-resistant generalised anxiety disorder: the FACTOID feasibility study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 54
• Published:
  16 September 2021

Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop

• Journal:
  Health Technology Assessment Volume: 25, Issue: 53
• Published:
  9 September 2021

A prognostic model, including quantitative fetal fibronectin, to predict preterm labour: the QUIDS meta-analysis and prospective cohort study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 52
• Published:
  8 September 2021

Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results

• Journal:
  Health Technology Assessment Volume: 25, Issue: 51
• Published:
  25 August 2021

Cardiovascular disease risk communication in NHS Health Checks using QRISK®2 and JBS3 risk calculators: the RICO qualitative and quantitative study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 50
• Published:
  24 August 2021

Practice nurse-supported weight self-management delivered within the national child immunisation programme for postnatal women: a feasibility cluster RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 49
• Published:
  12 August 2021

Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 48
• Published:
  12 August 2021

Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 47
• Published:
  28 July 2021

Home environmental assessments and modification delivered by occupational therapists to reduce falls in people aged 65 years and over: the OTIS RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 46
• Published:
  13 July 2021

Prognostic biomarkers to identify patients likely to develop severe Crohn's disease: a systematic review

• Journal:
  Health Technology Assessment Volume: 25, Issue: 45
• Published:
  5 July 2021

The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 44
• Published:
  5 July 2021

Cognitive behavioural therapy compared with standardised medical care for adults with dissociative non-epileptic seizures: the CODES RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 43
• Published:
  1 July 2021

Testing strategies for Lynch syndrome in people with endometrial cancer: systematic reviews and economic evaluation

• Journal:
  Health Technology Assessment Volume: 25, Issue: 42
• Published:
  25 June 2021

Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 41
• Published:
  24 June 2021

Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 40
• Published:
  22 June 2021

Modelling of hypothetical SARS-CoV-2 point of care tests for routine testing in residential care homes: rapid cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 25, Issue: 39
• Published:
  18 June 2021

Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 38
• Published:
  16 June 2021

Developing a reference protocol for structured expert elicitation in health-care decision-making: a mixed-methods study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 37
• Published:
  9 June 2021

Nutritional management in newborn babies receiving therapeutic hypothermia: two retrospective observational studies using propensity score matching

• Journal:
  Health Technology Assessment Volume: 25, Issue: 36
• Published:
  7 June 2021

Modelling tool to support decision-making in the NHS Health Check programme: workshops, systematic review and co-production with users

• Journal:
  Health Technology Assessment Volume: 25, Issue: 35
• Published:
  2 June 2021

Fall prevention interventions in primary care to reduce fractures and falls in people aged 70 years and over: the PreFIT three-arm cluster RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 34
• Published:
  2 June 2021

High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 25, Issue: 33
• Published:
  1 June 2021

Multimodal imaging interpreted by graders to detect re-activation of diabetic eye disease in previously treated patients: the EMERALD diagnostic accuracy study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 32
• Published:
  1 June 2021

Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 31
• Published:
  25 May 2021

A prognostic model to guide decision-making on timing of delivery in late preterm pre-eclampsia: the PEACOCK prospective cohort study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 30
• Published:
  21 May 2021

A video-feedback parenting intervention to prevent enduring behaviour problems in at-risk children aged 12-36 months: the Healthy Start, Happy Start RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 29
• Published:
  20 May 2021

Prognostic models of survival in patients with advanced incurable cancer: the PiPS2 observational study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 28
• Published:
  20 May 2021

Provision of the progestogen-only pill by community pharmacies as bridging contraception for women receiving emergency contraception: the Bridge-it RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 27
• Published:
  5 May 2021

Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 26
• Published:
  30 April 2021

Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 25
• Published:
  15 April 2021

Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 24
• Published:
  13 April 2021

Prognostic tools for identification of high risk in people with Crohn's disease: systematic review and cost-effectiveness study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 23
• Published:
  26 March 2021

Parent-delivered interventions used at home to improve eating, drinking and swallowing in children with neurodisability: the FEEDS mixed-methods study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 22
• Published:
  26 March 2021

Modelling of hypothetical SARS-CoV-2 point-of-care tests on admission to hospital from A&E: rapid cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 25, Issue: 21
• Published:
  24 March 2021

Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 20
• Published:
  24 March 2021

Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 19
• Published:
  23 March 2021

Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 18
• Published:
  22 March 2021

Bisphosphonates to reduce bone fractures in stage 3B+ chronic kidney disease: a propensity score-matched cohort study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 17
• Published:
  19 March 2021

The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs

• Journal:
  Health Technology Assessment Volume: 25, Issue: 16
• Published:
  12 March 2021

Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 25, Issue: 15
• Published:
  3 March 2021

Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 14
• Published:
  2 March 2021

Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 13
• Published:
  1 March 2021

A case management occupational health model to facilitate earlier return to work of NHS staff with common mental health disorders: a feasibility study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 12
• Published:
  26 February 2021

Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 11
• Published:
  25 February 2021

Conservative treatment for uncomplicated appendicitis in children: the CONTRACT feasibility study, including feasibility RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 10
• Published:
  24 February 2021

Cognitive behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis

• Journal:
  Health Technology Assessment Volume: 25, Issue: 9
• Published:
  24 February 2021

Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 25, Issue: 8
• Published:
  8 February 2021

Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 7
• Published:
  4 February 2021

Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 6
• Published:
  29 January 2021

Individualised placement and support programme for people unemployed because of chronic pain: a feasibility study and the InSTEP pilot RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 5
• Published:
  27 January 2021

Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 4
• Published:
  25 January 2021

Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT

• Journal:
  Health Technology Assessment Volume: 25, Issue: 3
• Published:
  22 January 2021

Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study

• Journal:
  Health Technology Assessment Volume: 25, Issue: 2
• Published:
  8 January 2021

Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies

• Journal:
  Health Technology Assessment Volume: 25, Issue: 1
• Published:
  7 January 2021