Health Technology Assessment

Volume 21 (2017)

81 issues

Extended Research Article

Surveillance versus ablation for incidentally diagnosed small renal tumours: the SURAB feasibility RCT

Naeem Soomro
,
Jan Lecouturier
,
Deborah D Stocken
,
Jing Shen
,
Ann Marie Hynes
,
Holly F Ainsworth
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 81
  • Published:
    22 December 2017

Extended Research Article

Interventions for hyperhidrosis in secondary care: a systematic review and value-of-information analysis

Ros Wade
,
Stephen Rice
,
Alexis Llewellyn
,
Eoin Moloney
,
Julie Jones-Diette
,
Julija Stoniute
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 80
  • Published:
    22 December 2017

Extended Research Article

Virtual chromoendoscopy for the real-time assessment of colorectal polyps in vivo: a systematic review and economic evaluation

Joanna Picot
,
Micah Rose
,
Keith Cooper
,
Karen Pickett
,
Joanne Lord
,
Petra Harris
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 79
  • Published:
    22 December 2017

Extended Research Article

Clinical effectiveness and cost-effectiveness of issuing longer versus shorter duration (3-month vs. 28-day) prescriptions in patients with chronic conditions: systematic review and economic modelling

Céline Miani
,
Adam Martin
,
Josephine Exley
,
Brett Doble
,
Ed Wilson
,
Rupert Payne
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 78
  • Published:
    21 December 2017

Extended Research Article

A novel peer-support intervention using motivational interviewing for breastfeeding maintenance:a UK feasibility study

Shantini Paranjothy
,
Lauren Copeland
,
Laura Merrett
,
Aimee Grant
,
Rhiannon Phillips
,
Nina Gobat
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 77
  • Published:
    21 December 2017

Extended Research Article

Self-management toolkit and delivery strategy for end-of-life pain: the mixed-methods feasibility study

Michael I Bennett
,
Matthew R Mulvey
,
Natasha Campling
,
Sue Latter
,
Alison Richardson
,
Hilary Bekker
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 76
  • Published:
    21 December 2017

Extended Research Article

Managing diabetes in people with dementia: a realist review

Frances Bunn
,
Claire Goodman
,
Peter Reece Jones
,
Bridget Russell
,
Daksha Trivedi
,
Alan Sinclair
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 75
  • Published:
    13 December 2017

Extended Research Article

Facet-joint injections for non-specific low back pain: a feasibility RCT

Saowarat Snidvongs
,
Rod S Taylor
,
Alia Ahmad
,
Simon Thomson
,
Manohar Sharma
,
Angela Farr
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 74
  • Published:
    12 December 2017

Extended Research Article

Home-based health promotion for older people with mild frailty: the HomeHealth intervention development and feasibility RCT

Kate Walters
,
Rachael Frost
,
Kalpa Kharicha
,
Christina Avgerinou
,
Benjamin Gardner
,
Federico Ricciardi
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 73
  • Published:
    7 December 2017

Extended Research Article

Preventing blood-borne virus infection in people who inject drugs in the UK: systematic review, stakeholder interviews, psychosocial intervention development and feasibility randomised controlled trial

Gail Gilchrist
,
Davina Swan
,
April Shaw
,
Ada Keding
,
Sarah Towers
,
Noel Craine
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 72
  • Published:
    5 December 2017

Extended Research Article

The clinical effectiveness and cost-effectiveness of treat-to-target strategies in rheumatoid arthritis: a systematic review and cost-effectiveness analysis

Allan Wailoo
,
Emma S Hock
,
Matt Stevenson
,
Marrissa Martyn-St James
,
Andrew Rawdin
,
Emma Simpson
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 71
  • Published:
    5 December 2017

Extended Research Article

A pragmatic multicentre randomised controlled trial comparing stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease: the eTHoS study

Angus JM Watson
,
Jonathan Cook
,
Jemma Hudson
,
Mary Kilonzo
,
Jessica Wood
,
Hanne Bruhn
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 70
  • Published:
    5 December 2017

Extended Research Article

Assessing the performance of methodological search filters to improve the efficiency of evidence information retrieval: five literature reviews and a qualitative study

Carol Lefebvre
,
Julie Glanville
,
Sophie Beale
,
Charles Boachie
,
Steven Duffy
,
Cynthia Fraser
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 69
  • Published:
    30 November 2017

Extended Research Article

A systematic review and economic evaluation of adalimumab and dexamethasone for treating non-infectious intermediate uveitis, posterior uveitis or panuveitis in adults

Hazel Squires
,
Edith Poku
,
Inigo Bermejo
,
Katy Cooper
,
John Stevens
,
Jean Hamilton
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 68
  • Published:
    29 November 2017

Extended Research Article

CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness

Katharine Bosanquet
,
Joy Adamson
,
Katie Atherton
,
Della Bailey
,
Catherine Baxter
,
Jules Beresford-Dent
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 67
  • Published:
    24 November 2017

Extended Research Article

Is whole-colon investigation by colonoscopy, computerised tomography colonography or barium enema necessary for all patients with colorectal cancer symptoms, and for which patients would flexible sigmoidoscopy suffice? A retrospective cohort study

Wendy Atkin
,
Kate Wooldrage
,
Urvi Shah
,
Kate Skinner
,
Jeremy P Brown
,
Willie Hamilton
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 66
  • Published:
    20 November 2017

Extended Research Article

A multicentre, randomised controlled trial of position during the late stages of labour in nulliparous women with an epidural: clinical effectiveness and an economic evaluation (BUMPES)

Debra Bick
,
Annette Briley
,
Peter Brocklehurst
,
Pollyanna Hardy
,
Edmund Juszczak
,
Lynn Lynch
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 65
  • Published:
    7 November 2017

Extended Research Article

Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people: systematic review and economic evaluation

Ana Duarte
,
Teumzghi Mebrahtu
,
Pedro Saramago Goncalves
,
Melissa Harden
,
Ruth Murphy
,
Stephen Palmer
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 64
  • Published:
    6 November 2017

Extended Research Article

Timing of surgical intervention for developmental dysplasia of the hip: a randomised controlled trial (Hip 'Op)

Charlotte L Williams
,
Susie Weller
,
Lisa Roberts
,
Isabel Reading
,
Andrew Cook
,
Louisa Little
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 63
  • Published:
    25 October 2017

Extended Research Article

The Age of BLood Evaluation (ABLE) randomised controlled trial: description of the UK-funded arm of the international trial, the UK cost-utility analysis and secondary analyses exploring factors associated with health-related quality of life and health-care costs during the 12-month follow-up

Timothy S Walsh
,
Simon Stanworth
,
Julia Boyd
,
David Hope
,
Sue Hemmatapour
,
Helen Burrows
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 62
  • Published:
    25 October 2017

Extended Research Article

Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis

Jason Waugh
,
Richard Hooper
,
Edmund Lamb
,
Stephen Robson
,
Andrew Shennan
,
Fiona Milne
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 61
  • Published:
    24 October 2017

Extended Research Article

Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica

Nefyn H Williams
,
Alison Jenkins
,
Nia Goulden
,
Zoe Hoare
,
Dyfrig A Hughes
,
Eifiona Wood
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 60
  • Published:
    24 October 2017

Extended Research Article

International multicentre randomised controlled trial of improvisational music therapy for children with autism spectrum disorder: TIME-A study

Mike J Crawford
,
Christian Gold
,
Helen Odell-Miller
,
Lavanya Thana
,
Sarah Faber
,
Jörg Assmus
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 59
  • Published:
    23 October 2017

Extended Research Article

Real-time modelling of a pandemic influenza outbreak

Paul J Birrell
,
Richard G Pebody
,
André Charlett
,
Xu-Sheng Zhang
,
Daniela De Angelis
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 58
  • Published:
    23 October 2017

Extended Research Article

The Asymptomatic Carotid Surgery Trial-2 (ACST-2): an ongoing randomised controlled trial comparing carotid endarterectomy with carotid artery stenting to prevent stroke

Richard Bulbulia
,
Alison Halliday
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 57
  • Published:
    11 October 2017

Extended Research Article

Certolizumab pegol and secukinumab for treating active psoriatic arthritis following inadequate response to disease-modifying antirheumatic drugs: a systematic review and economic evaluation

Mark Corbett
,
Fadi Chehadah
,
Mousumi Biswas
,
Thirimon Moe-Byrne
,
Stephen Palmer
,
Marta Soares
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 56
  • Published:
    4 October 2017

Extended Research Article

Provision of information about newborn screening antenatally: a sequential exploratory mixed-methods project

Fiona Ulph
,
Stuart Wright
,
Nimarta Dharni
,
Katherine Payne
,
Rebecca Bennett
,
Stephen Roberts
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 55
  • Published:
    2 October 2017

Extended Research Article

A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial

Peter Langhorne
,
Olivia Wu
,
Helen Rodgers
,
Ann Ashburn
,
Julie Bernhardt
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 54
  • Published:
    2 October 2017

Extended Research Article

A randomised controlled study of the effectiveness of breathing retraining exercises taught by a physiotherapist either by instructional DVD or in face-to-face sessions in the management of asthma in adults

Mike Thomas
,
Anne Bruton
,
Paul Little
,
Stephen Holgate
,
Amanda Lee
,
Lucy Yardley
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 53
  • Published:
    25 September 2017

Extended Research Article

Clinical and cost-effectiveness of beta interferon and glatiramer acetate for treating multiple sclerosis: systematic review and economic evaluation

GJ Melendez-Torres
,
Peter Auguste
,
Xavier Armoiry
,
Hendramoorthy Maheswaran
,
Rachel Court
,
Jason Madan
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 52
  • Published:
    15 September 2017

Extended Research Article

Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation

Tristan Snowsill
,
Helen Coelho
,
Nicola Huxley
,
Tracey Jones-Hughes
,
Simon Briscoe
,
Ian M Frayling
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 51
  • Published:
    12 September 2017

Extended Research Article

Cognitive-behaviour therapy for health anxiety in medical patients (CHAMP): a randomised controlled trial with outcomes to 5 years

Peter Tyrer
,
Paul Salkovskis
,
Helen Tyrer
,
Duolao Wang
,
Michael J Crawford
,
Simon Dupont
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 50
  • Published:
    7 September 2017

Extended Research Article

Amisulpride augmentation in clozapine-unresponsive schizophrenia (AMICUS): a double-blind, placebo-controlled, randomised trial of clinical effectiveness and cost-effectiveness

Thomas RE Barnes
,
Verity C Leeson
,
Carol Paton
,
Louise Marston
,
Linda Davies
,
William Whittaker
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 49
  • Published:
    4 September 2017

Extended Research Article

Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study

Hans de Graaf
,
Priya Sukhtankar
,
Barbara Arch
,
Nusreen Ahmad
,
Amanda Lees
,
Abigail Bennett
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 48
  • Published:
    1 September 2017

Extended Research Article

A pilot randomised controlled trial of community-led ANtipsychotic Drug REduction for Adults with Learning Disabilities

Rachel McNamara
,
Elizabeth Randell
,
David Gillespie
,
Fiona Wood
,
David Felce
,
Renee Romeo
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 47
  • Published:
    31 August 2017

Extended Research Article

Cost and Outcome of BehaviouRal Activation (COBRA): a randomised controlled trial of behavioural activation versus cognitive behavioural therapy for depression

David A Richards
,
Shelley Rhodes
,
David Ekers
,
Dean McMillan
,
Rod S Taylor
,
Sarah Byford
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 46
  • Published:
    31 August 2017

Extended Research Article

Pilot of a randomised controlled trial of the selective serotonin reuptake inhibitor sertraline versus cognitive behavioural therapy for anxiety symptoms in people with generalised anxiety disorder who have failed to respond to low-intensity psychological treatments as defined by the National Institute for Health and Care Excellence guidelines

Marta Buszewicz
,
John Cape
,
Marc Serfaty
,
Roz Shafran
,
Thomas Kabir
,
Peter Tyrer
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 45
  • Published:
    30 August 2017

Extended Research Article

Developing a multidisciplinary rehabilitation package following hip fracture and testing in a randomised feasibility study: Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR)

Nefyn H Williams
,
Jessica L Roberts
,
Nafees Ud Din
,
Joanna M Charles
,
Nicola Totton
,
Michelle Williams
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 44
  • Published:
    24 August 2017

Extended Research Article

Systematic review of interventions for treating or preventing antipsychotic-induced tardive dyskinesia

Hanna Bergman
,
Dawn-Marie Walker
,
Adriani Nikolakopoulou
,
Karla Soares-Weiser
,
Clive E Adams
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 43
  • Published:
    16 August 2017

Extended Research Article

Managing Faecal INcontinence in people with advanced dementia resident in Care Homes (FINCH) study: a realist synthesis of the evidence

Claire Goodman
,
Christine Norton
,
Marina Buswell
,
Bridget Russell
,
Danielle Harari
,
Rowan Harwood
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 42
  • Published:
    14 August 2017

Extended Research Article

Effects of antenatal diet and physical activity on maternal and fetal outcomes: individual patient data meta-analysis and health economic evaluation

Ewelina Rogozińska
,
Nadine Marlin
,
Louise Jackson
,
Girish Rayanagoudar
,
Anneloes E Ruifrok
,
Julie Dodds
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 41
  • Published:
    10 August 2017

Extended Research Article

Effectiveness and cost-effectiveness of serum B-type natriuretic peptide testing and monitoring in patients with heart failure in primary and secondary care: an evidence synthesis, cohort study and cost-effectiveness model

Maria Pufulete
,
Rachel Maishman
,
Lucy Dabner
,
Syed Mohiuddin
,
William Hollingworth
,
Chris A Rogers
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 40
  • Published:
    4 August 2017

Extended Research Article

Observational study to estimate the changes in the effectiveness of bacillus Calmette Guerin (BCG) vaccination with time since vaccination for preventing tuberculosis in the UK

Punam Mangtani
,
Patrick Nguipdop-Djomo
,
Ruth H Keogh
,
Lucy Trinder
,
Peter G Smith
,
Paul EM Fine
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 39
  • Published:
    24 July 2017

Extended Research Article

The clinical effectiveness and cost-effectiveness of cetuximab (review of technology appraisal no. 176) and panitumumab (partial review of technology appraisal no. 240) for previously untreated metastatic colorectal cancer: a systematic review and economic evaluation

Nicola Huxley
,
Louise Crathorne
,
Jo Varley-Campbell
,
Irina Tikhonova
,
Tristan Snowsill
,
Simon Briscoe
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 38
  • Published:
    4 July 2017

Extended Research Article

Clinical effectiveness, cost-effectiveness and acceptability of low-intensity interventions in the management of obsessive compulsive disorder: the Obsessive Compulsive Treatment Efficacy randomised controlled Trial (OCTET)

Karina Lovell
,
Peter Bower
,
Judith Gellatly
,
Sarah Byford
,
Penny Bee
,
Dean McMillan
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 37
  • Published:
    4 July 2017

Extended Research Article

Barriers to and facilitators of smoking cessation in pregnancy and following childbirth: literature review and qualitative study

Linda Bauld
,
Hilary Graham
,
Lesley Sinclair
,
Kate Flemming
,
Felix Naughton
,
Allison Ford
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 36
  • Published:
    29 June 2017

Extended Research Article

Debt Counselling for Depression in Primary Care: an adaptive randomised controlled pilot trial (DeCoDer study)

Mark B Gabbay
,
Adele Ring
,
Richard Byng
,
Pippa Anderson
,
Rod S Taylor
,
Caryn Matthews
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 35
  • Published:
    7 June 2017

Extended Research Article

Evaluation of the effectiveness and cost-effectiveness of lightweight fibreglass heel casts in the management of ulcers of the heel in diabetes: a randomised controlled trial

William Jeffcoate
,
Frances Game
,
Vivienne Turtle-Savage
,
Alison Musgrove
,
Patricia Price
,
Wei Tan
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 34
  • Published:
    2 June 2017

Extended Research Article

Faecal immunochemical tests to triage patients with lower abdominal symptoms for suspected colorectal cancer referrals in primary care: a systematic review and cost-effectiveness analysis

Marie Westwood
,
Isaac Corro Ramos
,
Shona Lang
,
Marianne Luyendijk
,
Remziye Zaim
,
Lisa Stirk
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 33
  • Published:
    2 June 2017

Extended Research Article

A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent

David Mant
,
Alastair Gray
,
Siân Pugh
,
Helen Campbell
,
Stephen George
,
Alice Fuller
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 32
  • Published:
    31 May 2017

Extended Research Article

A multicentre randomiSed controlled TRial of IntraVEnous immunoglobulin compared with standard therapy for the treatment of transverse myelitis in adults and children (STRIVE)

Michael Absoud
,
Peter Brex
,
Olga Ciccarelli
,
Onyinye Diribe
,
Gavin Giovannoni
,
Jennifer Hellier
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 31
  • Published:
    30 May 2017

Extended Research Article

Facet joint injections for people with persistent non-specific low back pain (Facet Injection Study): a feasibility study for a randomised controlled trial

David R Ellard
,
Martin Underwood
,
Felix Achana
,
James HL Antrobus
,
Shyam Balasubramanian
,
Sally Brown
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 30
  • Published:
    30 May 2017

Extended Research Article

Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis

Nicky J Welton
,
Alexandra McAleenan
,
Howard HZ Thom
,
Philippa Davies
,
Will Hollingworth
,
Julian PT Higgins
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 29
  • Published:
    27 May 2017

Extended Research Article

Clinical effectiveness and cost-effectiveness results from the randomised, Phase IIB trial in previously untreated patients with chronic lymphocytic leukaemia to compare fludarabine, cyclophosphamide and rituximab with fludarabine, cyclophosphamide, mitoxantrone and low-dose rituximab: the Attenuated dose Rituximab with ChemoTherapy In Chronic lymphocytic leukaemia (ARCTIC) trial

Dena R Howard
,
Talha Munir
,
Lucy McParland
,
Andy C Rawstron
,
Anna Chalmers
,
Walter M Gregory
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 28
  • Published:
    23 May 2017

Extended Research Article

Aquatic therapy for children with Duchenne muscular dystrophy: a pilot feasibility randomised controlled trial and mixed-methods process evaluation

Daniel Hind
,
James Parkin
,
Victoria Whitworth
,
Saleema Rex
,
Tracey Young
,
Lisa Hampson
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 27
  • Published:
    12 May 2017

Extended Research Article

Development of a core outcome set for disease modification trials in mild to moderate dementia: a systematic review, patient and public consultation and consensus recommendations

Lucy Webster
,
Derek Groskreutz
,
Anna Grinbergs-Saull
,
Rob Howard
,
John T O’Brien
,
Gail Mountain
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 26
  • Published:
    10 May 2017

Extended Research Article

The clinical effectiveness of different surveillance strategies to prevent colorectal cancer in people with intermediate-grade colorectal adenomas: a retrospective cohort analysis, and psychological and economic evaluations

Wendy Atkin
,
Amy Brenner
,
Jessica Martin
,
Katherine Wooldrage
,
Urvi Shah
,
Fiona Lucas
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 25
  • Published:
    3 May 2017

Extended Research Article

Clinical effectiveness and cost-effectiveness of a multifaceted podiatry intervention for falls prevention in older people: a multicentre cohort randomised controlled trial (the REducing Falls with ORthoses and a Multifaceted podiatry intervention trial)

Sarah Cockayne
,
Sara Rodgers
,
Lorraine Green
,
Caroline Fairhurst
,
Joy Adamson
,
Arabella Scantlebury
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 24
  • Published:
    3 May 2017

Extended Research Article

Multiplex tests to identify gastrointestinal bacteria, viruses and parasites in people with suspected infectious gastroenteritis: a systematic review and economic analysis

Karoline Freeman
,
Hema Mistry
,
Alexander Tsertsvadze
,
Pam Royle
,
Noel McCarthy
,
Sian Taylor-Phillips
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 23
  • Published:
    3 May 2017

Extended Research Article

What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up? A systematic review and secondary analysis of a randomised controlled trial

Bethany Shinkins
,
Brian D Nicholson
,
Tim James
,
Indika Pathiraja
,
Sian Pugh
,
Rafael Perera
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 22
  • Published:
    28 April 2017

Extended Research Article

Seal or Varnish? A randomised controlled trial to determine the relative cost and effectiveness of pit and fissure sealant and fluoride varnish in preventing dental decay

Ivor Gordon Chestnutt
,
Simon Hutchings
,
Rebecca Playle
,
Sarah Morgan-Trimmer
,
Deborah Fitzsimmons
,
Nadine Aawar
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 21
  • Published:
    28 April 2017

Extended Research Article

A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial

Simon Heller
,
David White
,
Ellen Lee
,
Julia Lawton
,
Daniel Pollard
,
Norman Waugh
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 20
  • Published:
    21 April 2017

Extended Research Article

Modifying Alcohol Consumption to Reduce Obesity (MACRO): development and feasibility trial of a complex community-based intervention for men

Iain K Crombie
,
Kathryn B Cunningham
,
Linda Irvine
,
Brian Williams
,
Falko F Sniehotta
,
John Norrie
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 19
  • Published:
    12 April 2017

Extended Research Article

Development and validation of Prediction models for Risks of complications in Early-onset Pre-eclampsia (PREP): a prospective cohort study

Shakila Thangaratinam
,
John Allotey
,
Nadine Marlin
,
Ben W Mol
,
Peter Von Dadelszen
,
Wessel Ganzevoort
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 18
  • Published:
    12 April 2017

Extended Research Article

PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer

Hisham Mehanna
,
Chris C McConkey
,
Joy K Rahman
,
Wai-Lup Wong
,
Alison F Smith
,
Chris Nutting
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 17
  • Published:
    12 April 2017

Extended Research Article

Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial

Kim S Thomas
,
Lucy E Bradshaw
,
Tracey H Sach
,
Fiona Cowdell
,
Jonathan M Batchelor
,
Sandra Lawton
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 16
  • Published:
    11 April 2017

Extended Research Article

Youth social behaviour and network therapy (Y-SBNT): adaptation of a family and social network intervention for young people who misuse alcohol and drugs a randomised controlled feasibility trial

Judith Watson
,
Paul Toner
,
Ed Day
,
Donna Back
,
Louca-Mai Brady
,
Caroline Fairhurst
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 15
  • Published:
    7 April 2017

Extended Research Article

Pre-conception care for women with type 1 or type 2 diabetes: A mixed methods study exploring uptake of pre-conception care

Sarah Earle
,
Anisah Tariq
,
Carol Komaromy
,
Cathy E Lloyd
,
M Ali Karamat
,
Jackie Webb
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 14
  • Published:
    7 April 2017

Extended Research Article

Support and Assessment for Fall Emergency Referrals (SAFER) 2: a cluster randomised trial and systematic review of clinical effectiveness and cost-effectiveness of new protocols for emergency ambulance paramedics to assess older people following a fall with referral to community-based care when appropriate

Helen A Snooks
,
Rebecca Anthony
,
Robin Chatters
,
Jeremy Dale
,
Rachael Fothergill
,
Sarah Gaze
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 13
  • Published:
    7 April 2017

Extended Research Article

Cognitive behavioural therapy and short-term psychoanalytic psychotherapy versus brief psychosocial intervention in adolescents with unipolar major depression (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled trial

Ian M Goodyer
,
Shirley Reynolds
,
Barbara Barrett
,
Sarah Byford
,
Bernadka Dubicka
,
Jonathan Hill
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 12
  • Published:
    7 April 2017

Extended Research Article

Prehospital randomised assessment of a mechanical compression device in out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised trial and economic evaluation

Simon Gates
,
Ranjit Lall
,
Tom Quinn
,
Charles D Deakin
,
Matthew W Cooke
,
Jessica Horton
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 11
  • Published:
    7 April 2017

Extended Research Article

A randomised controlled trial to compare the safety, effectiveness and cost effectiveness of doxycycline (200 mg/day) with oral prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid: the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) Trial

Joanne R Chalmers
,
Fenella Wojnarowska
,
Gudula Kirtschig
,
James Mason
,
Margaret Childs
,
Diane Whitham
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 10
  • Published:
    13 March 2017

Extended Research Article

Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis

Jonathan AC Sterne
,
Pritesh N Bodalia
,
Peter A Bryden
,
Philippa A Davies
,
Jose A López-López
,
George N Okoli
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 9
  • Published:
    10 March 2017

Extended Research Article

CollAborative care and active surveillance for Screen-Positive EldeRs with subthreshold depression (CASPER): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness

Helen Lewis
,
Joy Adamson
,
Katie Atherton
,
Della Bailey
,
Jacqueline Birtwistle
,
Katharine Bosanquet
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 8
  • Published:
    1 March 2017

Extended Research Article

The assessment and appraisal of regenerative medicines and cell therapy products: an exploration of methods for review, economic evaluation and appraisal

Robert Hettle
,
Mark Corbett
,
Sebastian Hinde
,
Robert Hodgson
,
Julie Jones-Diette
,
Nerys Woolacott
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 7
  • Published:
    1 March 2017

Extended Research Article

Autologous chondrocyte implantation in the knee: systematic review and economic evaluation

Hema Mistry
,
Martin Connock
,
Joshua Pink
,
Deepson Shyangdan
,
Christine Clar
,
Pamela Royle
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 6
  • Published:
    13 February 2017

Extended Research Article

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development

Paul Flowers
,
Olivia Wu
,
Karen Lorimer
,
Bipasha Ahmed
,
Hannah Hesselgreaves
,
Jennifer MacDonald
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 5
  • Published:
    1 February 2017

Extended Research Article

Randomised controlled trial and economic analysis of an internet-based weight management programme: POWeR+ (Positive Online Weight Reduction)

Paul Little
,
Beth Stuart
,
FD Richard Hobbs
,
Jo Kelly
,
Emily R Smith
,
Katherine J Bradbury
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 4
  • Published:
    25 January 2017

Extended Research Article

Start2quit: a randomised clinical controlled trial to evaluate the effectiveness and cost-effectiveness of using personal tailored risk information and taster sessions to increase the uptake of the NHS Stop Smoking Services

Hazel Gilbert
,
Stephen Sutton
,
Richard Morris
,
Irene Petersen
,
Qi Wu
,
Steve Parrott
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 3
  • Published:
    25 January 2017

Extended Research Article

Canagliflozin, dapagliflozin and empagliflozin monotherapy for treating type 2 diabetes: systematic review and economic evaluation

Rhona Johnston
,
Olalekan Uthman
,
Ewen Cummins
,
Christine Clar
,
Pamela Royle
,
Jill Colquitt
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 2
  • Published:
    20 January 2017

Extended Research Article

Randomised controlled trial evaluating the effectiveness and cost-effectiveness of 'Families for Health', a family-based childhood obesity treatment intervention delivered in a community setting for ages 6 to 11 years

Wendy Robertson
,
Joanna Fleming
,
Atiya Kamal
,
Thomas Hamborg
,
Kamran A Khan
,
Frances Griffiths
et al.
  • Journal:
    Health Technology Assessment Volume: 21, Issue: 1
  • Published:
    6 January 2017