Health Technology Assessment - Volume 28

Extended Research Article

Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis

Nicola Curry

,

Ross Davenport

,

Helen Thomas

,

Erin Fox

,

Joanne Lucas

,

Amy Evans

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 76
Published:

14 November 2024

Extended Research Article

Genedrive kit for detecting single nucleotide polymorphism m.1555A>G in neonates and their mothers: a systematic review and cost-effectiveness analysis

Hosein Shabaninejad

,

Ryan PW Kenny

,

Tomos Robinson

,

Akvile Stoniute

,

Hannah O’Keefe

,

Madeleine Still

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 75
Published:

31 October 2024

Extended Research Article

Take-home naloxone in multicentre emergency settings: the TIME feasibility cluster RCT

Helen Snooks

,

Jonathan Benger

,

Fiona Bell

,

Sarah Black

,

Simon Dixon

,

Helena Emery

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 74
Published:

31 October 2024

Extended Research Article

Ceftazidime with avibactam for treating severe aerobic Gram-negative bacterial infections: technology evaluation to inform a novel subscription-style payment model

Sue Harnan

,

Ben Kearns

,

Alison Scope

,

Laetitia Schmitt

,

Dina Jankovic

,

Jean Hamilton

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 73
Published:

31 October 2024

Extended Research Article

Behavioural interventions to treat anxiety in adults with autism and moderate to severe intellectual disabilities: the BEAMS-ID feasibility study

Peter E Langdon

,

Magdalena M Apanasionok

,

Emma Scripps

,

Karen Bunning

,

Malwina Filipczuk

,

David Gillespie

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 72
Published:

31 October 2024

Extended Research Article

Timing of Stoma Closure in Neonates: the ToSCiN mixed-methods study

Nick Lansdale

,

Kerry Woolfall

,

Elizabeth Deja

,

Tracy Mitchell

,

Graciaa Singhal

,

Raphael Goldacre

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 71
Published:

31 October 2024

Extended Research Article

Comparison of cognitive behaviour therapy versus activity management, both delivered remotely, to treat paediatric chronic fatigue syndrome/myalgic encephalomyelitis: the UK FITNET-NHS RCT

Esther Crawley

,

Emma Anderson

,

Madeleine Cochrane

,

Beverly A Shirkey

,

Roxanne Parslow

,

William Hollingworth

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 70
Published:

31 October 2024

Extended Research Article

Interventions for people with perceptual disorders after stroke: the PIONEER scoping review, Cochrane systematic review and priority setting project

Christine Hazelton

,

Alex Todhunter-Brown

,

Pauline Campbell

,

Katie Thomson

,

Donald J Nicolson

,

Kris McGill

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 69
Published:

31 October 2024

Extended Research Article

Strategies for older people living in care homes to prevent urinary tract infection: the StOP UTI realist synthesis

Jacqui Prieto

,

Jennie Wilson

,

Alison Tingle

,

Emily Cooper

,

Melanie Handley

,

Jo Rycroft-Malone

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 68
Published:

17 October 2024

Extended Research Article

Care models for coexisting serious mental health and alcohol/drug conditions: the RECO realist evidence synthesis and case study evaluation

Elizabeth Hughes

,

Jane Harris

,

Tom Ainscough

,

Angela Bate

,

Alex Copello

,

Sonia Dalkin

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 67
Published:

9 October 2024

Extended Research Article

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT

Alexandra Wright-Hughes

,

Alexander C Ford

,

Sarah L Alderson

,

Pei Loo Ow

,

Matthew J Ridd

,

Robbie Foy

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 66
Published:

9 October 2024

Extended Research Article

Vein bypass first vs. best endovascular treatment first revascularisation strategy for chronic limb-threatening ischaemia due to infra-popliteal disease: the BASIL-2 RCT

Catherine A Moakes

,

Andrew W Bradbury

,

Zainab Abdali

,

Gareth R Bate

,

Jack Hall

,

Hugh Jarrett

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 65
Published:

9 October 2024

Extended Research Article

Specific phobias in children with moderate to severe intellectual disabilities: SPIRIT, an adaptation and feasibility study

Kylie M Gray

,

Magdalena M Apanasionok

,

Emma Scripps

,

Karen Bunning

,

Christine Burke

,

Malwina Filipczuk

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 64
Published:

3 October 2024

Extended Research Article

Preventive drug treatments for adults with chronic migraine: a systematic review with economic modelling

Hema Mistry

,

Seyran Naghdi

,

Anna Brown

,

Sophie Rees

,

Jason Madan

,

Amy Grove

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 63
Published:

3 October 2024

Extended Research Article

Antidepressants for pain management in adults with chronic pain: a network meta-analysis

Hollie Birkinshaw

,

Claire Friedrich

,

Peter Cole

,

Christopher Eccleston

,

Marc Serfaty

,

Gavin Stewart

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 62
Published:

3 October 2024

Extended Research Article

MRI software and cognitive fusion biopsies in people with suspected prostate cancer: a systematic review, network meta-analysis and cost-effectiveness analysis

Alexis Llewellyn

,

Thai Han Phung

,

Marta O Soares

,

Lucy Shepherd

,

David Glynn

,

Melissa Harden

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 61
Published:

3 October 2024

Extended Research Article

Transperineal biopsy devices in people with suspected prostate cancer - a systematic review and economic evaluation

Inês Souto-Ribeiro

,

Lois Woods

,

Emma Maund

,

David Alexander Scott

,

Joanne Lord

,

Joanna Picot

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 60
Published:

3 October 2024

Extended Research Article

Alitretinoin versus phototherapy as the first-line treatment in adults with severe chronic hand eczema: the ALPHA RCT

Miriam Wittmann

,

Isabelle L Smith

,

Sarah Tess Brown

,

Anna Berekméri

,

Armando Vargas-Palacios

,

Lesley Sunderland

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 59
Published:

3 October 2024

Extended Research Article

The effect of two speech and language approaches on speech problems in people with Parkinson's disease: the PD COMM RCT

Catherine M Sackley

,

Caroline Rick

,

Marian C Brady

,

Christopher Burton

,

Sue Jowett

,

Smitaa Patel

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 58
Published:

3 October 2024

Extended Research Article

Clinical and cost-effectiveness of clopidogrel resistance genotype testing after ischaemic stroke or transient ischaemic attack: a systematic review and economic model

Joe Carroll

,

Catalina Lopez Manzano

,

Eve Tomlinson

,

Ayman Sadek

,

Chris Cooper

,

Hayley E Jones

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 57
Published:

12 September 2024

Extended Research Article

Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT

Miriam Santer

,

Megan Lawrence

,

Sarah Pyne

,

Susanne Renz

,

Beth L Stuart

,

Tracey Sach

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 56
Published:

12 September 2024

Extended Research Article

Preventing recurrence of endometriosis-related pain by means of long-acting progestogen therapy: the PRE-EMPT RCT

Kevin G Cooper

,

Siladitya Bhattacharya

,

Jane P Daniels

,

Versha Cheed

,

Laura Gennard

,

Lisa Leighton

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 55
Published:

5 September 2024

Extended Research Article

The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: the (UK-REBOA) multicentre RCT

Jan O Jansen

,

Jemma Hudson

,

Charlotte Kennedy

,

Claire Cochran

,

Graeme MacLennan

,

Katie Gillies

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 54
Published:

5 September 2024

Extended Research Article

Chair-based yoga programme for older adults with multimorbidity: RCT with embedded economic and process evaluations

Garry Alan Tew

,

Laura Wiley

,

Lesley Ward

,

Jessica Grace Hugill-Jones

,

Camila Sofia Maturana

,

Caroline Marie Fairhurst

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 53
Published:

5 September 2024

Extended Research Article

Behaviour change intervention (education and text) to prevent dental caries in secondary school pupils: BRIGHT RCT, process and economic evaluation

Zoe Marshman

,

Hannah Ainsworth

,

Caroline Fairhurst

,

Katie Whiteside

,

Debbie Sykes

,

Anju Keetharuth

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 52
Published:

5 September 2024

Extended Research Article

Hyperthermic intraoperative peritoneal chemotherapy and cytoreductive surgery for people with peritoneal metastases: a systematic review and cost-effectiveness analysis

Kurinchi Gurusamy

,

Jeffrey Leung

,

Claire Vale

,

Danielle Roberts

,

Audrey Linden

,

Xiao Wei Tan

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 51
Published:

5 September 2024

Extended Research Article

Artificial intelligence software for analysing chest X-ray images to identify suspected lung cancer: an evidence synthesis early value assessment

Jill Colquitt

,

Mary Jordan

,

Rachel Court

,

Emma Loveman

,

Janette Parr

,

Iman Ghosh

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 50
Published:

29 August 2024

Extended Research Article

Lenvatinib plus pembrolizumab for untreated advanced renal cell carcinoma: a systematic review and cost-effectiveness analysis

Nigel Fleeman

,

Rachel Houten

,

Sarah Nevitt

,

James Mahon

,

Sophie Beale

,

Angela Boland

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 49
Published:

29 August 2024

Extended Research Article

Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis

Thomas Frederick Crocker

,

Natalie Lam

,

Joie Ensor

,

Magda Jordão

,

Ram Bajpai

,

Matthew Bond

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 48
Published:

28 August 2024

Extended Research Article

Development and validation of prediction models for fetal growth restriction and birthweight: an individual participant data meta-analysis

John Allotey

,

Lucinda Archer

,

Dyuti Coomar

,

Kym IE Snell

,

Melanie Smuk

,

Lucy Oakey

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 47
Published:

29 August 2024

Extended Research Article

Real-time ultrasound elastography in the diagnosis of newly identified thyroid nodules in adults: the ElaTION RCT

Hisham Mehanna

,

Jonathan J Deeks

,

Kristien Boelaert

,

Gitta Madani

,

Paul Sidhu

,

Paul Nankivell

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 46
Published:

29 August 2024

Extended Research Article

Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer: the STAR non-inferiority RCT

Fiona Collinson

,

Kara-Louise Royle

,

Jayne Swain

,

Christy Ralph

,

Anthony Maraveyas

,

Tim Eisen

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 45
Published:

29 August 2024

Extended Research Article

Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

Carrie Stewart

,

Hangjian Wu

,

Uma Alagappan

,

Augusto Azuara-Blanco

,

Anthony J King

,

Andrew J Tatham

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 44
Published:

29 August 2024

Extended Research Article

The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation

Moira Cruickshank

,

Jemma Hudson

,

Rodolfo Hernández

,

Magaly Aceves-Martins

,

Richard Quinton

,

Katie Gillies

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 43
Published:

29 August 2024

Extended Research Article

Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT

Nicholas James

,

Sarah Pirrie

,

Wenyu Liu

,

James Catto

,

Kieran Jefferson

,

Prashant Patel

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 42
Published:

29 August 2024

Extended Research Article

Gynaecological cancer surveillance for women with Lynch syndrome: systematic review and cost-effectiveness evaluation

Tristan M Snowsill

,

Helen Coelho

,

Nia G Morrish

,

Simon Briscoe

,

Kate Boddy

,

Tracy Smith

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 41
Published:

29 August 2024

Extended Research Article

Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT

Victoria Hodgetts Morton

,

Catherine A Moakes

,

Jane Daniels

,

Lee Middleton

,

Andrew Shennan

,

Peter Brocklehurst

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 40
Published:

29 August 2024

Extended Research Article

Impact of Social Stories on social and emotional health of autism spectrum primary school children: the ASSSIST2 RCT with economic evaluation

Barry Wright

,

Kerry Jane Bell

,

Jane E Blackwell

,

Catarina Teige

,

Laura Mandefield

,

Han I Wang

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 39
Published:

22 August 2024

Extended Research Article

Clinical and cost-effectiveness of left ventricular assist devices as destination therapy for advanced heart failure: systematic review and economic evaluation

Sophie Beese

,

Tuba S Avşar

,

Malcolm Price

,

David Quinn

,

Hoong S Lim

,

Janine Dretzke

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 38
Published:

15 August 2024

Extended Research Article

Automated devices for identifying peripheral arterial disease in people with leg ulceration: an evidence synthesis and cost-effectiveness analysis

Dwayne Boyers

,

Moira Cruickshank

,

Lorna Aucott

,

Charlotte Kennedy

,

Paul Manson

,

Paul Bachoo

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 37
Published:

15 August 2024

Extended Research Article

Nurse-delivered sleep restriction therapy to improve insomnia disorder in primary care: the HABIT RCT

Simon D Kyle

,

Peter Bower

,

Ly-Mee Yu

,

Aloysius Niroshan Siriwardena

,

Yaling Yang

,

Stavros Petrou

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 36
Published:

15 August 2024

Extended Research Article

Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study

Edmund J Lamb

,

Jonathan Barratt

,

Elizabeth A Brettell

,

Paul Cockwell

,

R Nei Dalton

,

Jon J Deeks

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 35
Published:

25 July 2024

Extended Research Article

Immunogenicity and seroefficacy of pneumococcal conjugate vaccines: a systematic review and network meta-analysis

Shuo Feng

,

Julie McLellan

,

Nicola Pidduck

,

Nia Roberts

,

Julian PT Higgins

,

Yoon Choi

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 34
Published:

17 July 2024

Extended Research Article

Treatment options for patients with pilonidal sinus disease: PITSTOP, a mixed-methods evaluation

Steven Brown

,

Daniel Hind

,

Emily Strong

,

Mike Bradburn

,

Farhat Vanessa Nasim Din

,

Ellen Lee

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 33
Published:

17 July 2024

Extended Research Article

Home-monitoring for neovascular age related macular degeneration in older adults within the UK: the MONARCH diagnostic accuracy study

Ruth E Hogg

,

Robin Wickens

,

Sean O’Connor

,

Eleanor Gidman

,

Elizabeth Ward

,

Charlene Treanor

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 32
Published:

11 July 2024

Extended Research Article

A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model

Marie Westwood

,

Nigel Armstrong

,

Eline Krijkamp

,

Mark Perry

,

Caro Noake

,

Apostolos Tsiachristas

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 31
Published:

11 July 2024

Extended Research Article

Devices for remote continuous monitoring of people with Parkinson's disease: a systematic review and cost-effectiveness analysis

Edward Cox

,

Ros Wade

,

Robert Hodgson

,

Helen Fulbright

,

Thai Han Phung

,

Nicholas Meader

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 30
Published:

11 July 2024

Extended Research Article

Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT

Lucy E Bradshaw

,

Laura A Wyatt

,

Sara J Brown

,

Rachel H Haines

,

Alan A Montgomery

,

Michael R Perkin

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 29
Published:

11 July 2024

Extended Research Article

Cefiderocol for treating severe aerobic Gram-negative bacterial infections: technology evaluation to inform a novel subscription-style payment model

Beth Woods

,

Laetitia Schmitt

,

Dina Jankovic

,

Benjamin Kearns

,

Alison Scope

,

Shijie Ren

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 28
Published:

27 June 2024

Extended Research Article

Comparison of surgical or non-surgical management for non-acute anterior cruciate ligament injury: the ACL SNNAP RCT

David J Beard

,

Loretta Davies

,

Jonathan A Cook

,

Jamie Stokes

,

Jose Leal

,

Heidi Fletcher

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 27
Published:

27 June 2024

Extended Research Article

Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

Karen Innes

,

Irfan Ahmed

,

Jemma Hudson

,

Rodolfo Hernández

,

Katie Gillies

,

Rebecca Bruce

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 26
Published:

27 June 2024

Extended Research Article

Benefits and harms of antenatal and newborn screening programmes in health economic assessments: the VALENTIA systematic review and qualitative investigation

Oliver Rivero-Arias

,

May Ee Png

,

Ashley White

,

Miaoqing Yang

,

Sian Taylor-Phillips

,

Lisa Hinton

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 25
Published:

27 June 2024

Extended Research Article

Doppler ultrasound surveillance of recently formed haemodialysis arteriovenous fistula: the SONAR observational cohort study

James Richards

,

Dominic Summers

,

Anna Sidders

,

Elisa Allen

,

Mohammed Ayaz Hossain

,

Subhankar Paul

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 24
Published:

16 May 2024

Extended Research Article

Clinical and cost-effectiveness of pessary self-management versus clinic-based care for pelvic organ prolapse in women: the TOPSY RCT with process evaluation

Carol Bugge

,

Suzanne Hagen

,

Andrew Elders

,

Helen Mason

,

Kirsteen Goodman

,

Melanie Dembinsky

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 23
Published:

16 May 2024

Extended Research Article

Advice only versus advice and a physiotherapy programme for acute traumatic anterior shoulder dislocation: the ARTISAN RCT

Rebecca Kearney

,

David Ellard

,

Helen Parsons

,

Aminul Haque

,

James Mason

,

Henry Nwankwo

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 22
Published:

30 April 2024

Extended Research Article

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study

Opinder Sahota

,

Melanie Narayanasamy

,

Anastasios Bastounis

,

Zoe Paskins

,

Simon Bishop

,

Tessa Langley

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 21
Published:

9 April 2024

Extended Research Article

Evaluation of venous thromboembolism risk assessment models for hospital inpatients: the VTEAM evidence synthesis

Daniel Edward Horner

,

Sarah Davis

,

Abdullah Pandor

,

Helen Shulver

,

Steve Goodacre

,

Daniel Hind

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 20
Published:

9 April 2024

Extended Research Article

KardiaMobile 6L for measuring QT interval in people having antipsychotic medication to inform early value assessment: a systematic review

Marie Westwood

,

Nigel Armstrong

,

Pawel Posadzki

,

Caro Noake

Journal:

Health Technology Assessment Volume: 28, Issue: 19
Published:

27 March 2024

Extended Research Article

Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease: the ALL-HEART RCT and economic evaluation

Isla S Mackenzie

,

Christopher J Hawkey

,

Ian Ford

,

Nicola Greenlaw

,

Filippo Pigazzani

,

Amy Rogers

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 18
Published:

27 March 2024

Extended Research Article

Patient-reported outcome measures for monitoring primary care patients with depression: the PROMDEP cluster RCT and economic evaluation

Tony Kendrick

,

Christopher Dowrick

,

Glyn Lewis

,

Michael Moore

,

Geraldine M Leydon

,

Adam WA Geraghty

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 17
Published:

27 March 2024

Extended Research Article

Prehospital early warning scores for adults with suspected sepsis: the PHEWS observational cohort and decision-analytic modelling study

Steve Goodacre

,

Laura Sutton

,

Kate Ennis

,

Ben Thomas

,

Olivia Hawksworth

,

Khurram Iftikhar

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 16
Published:

27 March 2024

Extended Research Article

Surgical versus non-surgical management of lateral compression type-1 pelvic fracture in adults 60 years and older: the L1FE RCT

Elizabeth Cook

,

Joanne Laycock

,

Dhanupriya Sivapathasuntharam

,

Camila Maturana

,

Catherine Hilton

,

Laura Doherty

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 15
Published:

19 March 2024

Extended Research Article

Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis: the EASI-SWITCH RCT

Vicky Coyle

,

Caroline Forde

,

Richard Adams

,

Ashley Agus

,

Rosemary Barnes

,

Ian Chau

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 14
Published:

19 March 2024

Extended Research Article

Lower urinary tract symptoms in men: the TRIUMPH cluster RCT

Jo Worthington

,

Jessica Frost

,

Emily Sanderson

,

Madeleine Cochrane

,

Jessica Wheeler

,

Nikki Cotterill

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 13
Published:

19 March 2024

Extended Research Article

A randomised, double blind, placebo-controlled trial of a two-week course of dexamethasone for adult patients with a symptomatic Chronic Subdural Haematoma (Dex-CSDH trial)

Peter J Hutchinson

,

Ellie Edlmann

,

John G Hanrahan

,

Diederik Bulters

,

Ardalan Zolnourian

,

Patrick Holton

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 12
Published:

19 March 2024

Extended Research Article

Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis

Marie Westwood

,

Bram Ramaekers

,

Sabine Grimm

,

Nigel Armstrong

,

Ben Wijnen

,

Charlotte Ahmadu

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 11
Published:

19 March 2024

Extended Research Article

Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT

Sean Carrie

,

Tony Fouweather

,

Tara Homer

,

James O’Hara

,

Nikki Rousseau

,

Leila Rooshenas

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 10
Published:

12 March 2024

Extended Research Article

Thromboprophylaxis during pregnancy and the puerperium: a systematic review and economic evaluation to estimate the value of future research

Sarah Davis

,

Abdullah Pandor

,

Fiona C Sampson

,

Jean Hamilton

,

Catherine Nelson-Piercy

,

Beverley J Hunt

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 9
Published:

5 March 2024

Extended Research Article

Use of selective gut decontamination in critically ill children: PICnIC a pilot RCT and mixed-methods study

Alanna Brown

,

Paloma Ferrando-Vivas

,

Mariana Popa

,

Gema Milla de la Fuente

,

John Pappachan

,

Brian H Cuthbertson

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 8
Published:

27 February 2024

Extended Research Article

Clinical outcomes and adverse events of bariatric surgery in adults with severe obesity in Scotland: the SCOTS observational cohort study

Ruth M Mackenzie

,

Abdulmajid Ali

,

Duff Bruce

,

Julie Bruce

,

Ian Ford

,

Nicola Greenlaw

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 7
Published:

30 January 2024

Extended Research Article

Clinical and cost-effectiveness of an adapted intervention for preschoolers with moderate to severe intellectual disabilities displaying behaviours that challenge: the EPICC-ID RCT

Tamara Ondruskova

,

Rachel Royston

,

Michael Absoud

,

Gareth Ambler

,

Chen Qu

,

Jacqueline Barnes

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 6
Published:

30 January 2024

Extended Research Article

Strategies used for childhood chronic functional constipation: the SUCCESS evidence synthesis

Alex Todhunter-Brown

,

Lorna Booth

,

Pauline Campbell

,

Brenda Cheer

,

Julie Cowie

,

Andrew Elders

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 5
Published:

30 January 2024

Extended Research Article

Abrocitinib, tralokinumab and upadacitinib for treating moderate-to-severe atopic dermatitis

Steven J Edwards

,

Charlotta Karner

,

Tracey Jhita

,

Samantha Barton

,

Gemma Marceniuk

,

Zenas Z N Yiu

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 4
Published:

30 January 2024

Extended Research Article

Development and evaluation of a de-escalation training intervention in adult acute and forensic units: the EDITION systematic review and feasibility trial

Owen Price

,

Cat Papastavrou Brooks

,

Isobel Johnston

,

Peter McPherson

,

Helena Goodman

,

Andrew Grundy

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 3
Published:

30 January 2024

Extended Research Article

Undertaking Studies Within A Trial to evaluate recruitment and retention strategies for randomised controlled trials: lessons learnt from the PROMETHEUS research programme

Adwoa Parker

,

Catherine Arundel

,

Laura Clark

,

Elizabeth Coleman

,

Laura Doherty

,

Catherine Elizabeth Hewitt

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 2
Published:

23 January 2024

Extended Research Article

A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation

Ratna Sohanpal

,

Hilary Pinnock

,

Liz Steed

,

Karen Heslop-Marshall

,

Moira J Kelly

,

Claire Chan

et al.

Journal:

Health Technology Assessment Volume: 28, Issue: 1
Published:

16 January 2024

Volume 28 (2024)

76 issues

Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis

Genedrive kit for detecting single nucleotide polymorphism m.1555A>G in neonates and their mothers: a systematic review and cost-effectiveness analysis

Take-home naloxone in multicentre emergency settings: the TIME feasibility cluster RCT

Ceftazidime with avibactam for treating severe aerobic Gram-negative bacterial infections: technology evaluation to inform a novel subscription-style payment model

Behavioural interventions to treat anxiety in adults with autism and moderate to severe intellectual disabilities: the BEAMS-ID feasibility study

Timing of Stoma Closure in Neonates: the ToSCiN mixed-methods study

Comparison of cognitive behaviour therapy versus activity management, both delivered remotely, to treat paediatric chronic fatigue syndrome/myalgic encephalomyelitis: the UK FITNET-NHS RCT

Interventions for people with perceptual disorders after stroke: the PIONEER scoping review, Cochrane systematic review and priority setting project

Strategies for older people living in care homes to prevent urinary tract infection: the StOP UTI realist synthesis

Care models for coexisting serious mental health and alcohol/drug conditions: the RECO realist evidence synthesis and case study evaluation

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT

Vein bypass first vs. best endovascular treatment first revascularisation strategy for chronic limb-threatening ischaemia due to infra-popliteal disease: the BASIL-2 RCT

Specific phobias in children with moderate to severe intellectual disabilities: SPIRIT, an adaptation and feasibility study

Preventive drug treatments for adults with chronic migraine: a systematic review with economic modelling

Antidepressants for pain management in adults with chronic pain: a network meta-analysis

MRI software and cognitive fusion biopsies in people with suspected prostate cancer: a systematic review, network meta-analysis and cost-effectiveness analysis

Transperineal biopsy devices in people with suspected prostate cancer - a systematic review and economic evaluation

Alitretinoin versus phototherapy as the first-line treatment in adults with severe chronic hand eczema: the ALPHA RCT

The effect of two speech and language approaches on speech problems in people with Parkinson's disease: the PD COMM RCT

Clinical and cost-effectiveness of clopidogrel resistance genotype testing after ischaemic stroke or transient ischaemic attack: a systematic review and economic model

Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT

Preventing recurrence of endometriosis-related pain by means of long-acting progestogen therapy: the PRE-EMPT RCT

The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: the (UK-REBOA) multicentre RCT

Chair-based yoga programme for older adults with multimorbidity: RCT with embedded economic and process evaluations

Behaviour change intervention (education and text) to prevent dental caries in secondary school pupils: BRIGHT RCT, process and economic evaluation

Hyperthermic intraoperative peritoneal chemotherapy and cytoreductive surgery for people with peritoneal metastases: a systematic review and cost-effectiveness analysis

Artificial intelligence software for analysing chest X-ray images to identify suspected lung cancer: an evidence synthesis early value assessment

Lenvatinib plus pembrolizumab for untreated advanced renal cell carcinoma: a systematic review and cost-effectiveness analysis

Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis

Development and validation of prediction models for fetal growth restriction and birthweight: an individual participant data meta-analysis

Real-time ultrasound elastography in the diagnosis of newly identified thyroid nodules in adults: the ElaTION RCT

Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer: the STAR non-inferiority RCT

Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation

Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT

Gynaecological cancer surveillance for women with Lynch syndrome: systematic review and cost-effectiveness evaluation

Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT

Impact of Social Stories on social and emotional health of autism spectrum primary school children: the ASSSIST2 RCT with economic evaluation

Clinical and cost-effectiveness of left ventricular assist devices as destination therapy for advanced heart failure: systematic review and economic evaluation

Automated devices for identifying peripheral arterial disease in people with leg ulceration: an evidence synthesis and cost-effectiveness analysis

Nurse-delivered sleep restriction therapy to improve insomnia disorder in primary care: the HABIT RCT

Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study

Immunogenicity and seroefficacy of pneumococcal conjugate vaccines: a systematic review and network meta-analysis

Treatment options for patients with pilonidal sinus disease: PITSTOP, a mixed-methods evaluation

Home-monitoring for neovascular age related macular degeneration in older adults within the UK: the MONARCH diagnostic accuracy study

A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model

Devices for remote continuous monitoring of people with Parkinson's disease: a systematic review and cost-effectiveness analysis

Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT

Cefiderocol for treating severe aerobic Gram-negative bacterial infections: technology evaluation to inform a novel subscription-style payment model

Comparison of surgical or non-surgical management for non-acute anterior cruciate ligament injury: the ACL SNNAP RCT

Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

Benefits and harms of antenatal and newborn screening programmes in health economic assessments: the VALENTIA systematic review and qualitative investigation

Doppler ultrasound surveillance of recently formed haemodialysis arteriovenous fistula: the SONAR observational cohort study

Clinical and cost-effectiveness of pessary self-management versus clinic-based care for pelvic organ prolapse in women: the TOPSY RCT with process evaluation

Advice only versus advice and a physiotherapy programme for acute traumatic anterior shoulder dislocation: the ARTISAN RCT

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study

Evaluation of venous thromboembolism risk assessment models for hospital inpatients: the VTEAM evidence synthesis

KardiaMobile 6L for measuring QT interval in people having antipsychotic medication to inform early value assessment: a systematic review

Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease: the ALL-HEART RCT and economic evaluation

Patient-reported outcome measures for monitoring primary care patients with depression: the PROMDEP cluster RCT and economic evaluation

Prehospital early warning scores for adults with suspected sepsis: the PHEWS observational cohort and decision-analytic modelling study

Surgical versus non-surgical management of lateral compression type-1 pelvic fracture in adults 60 years and older: the L1FE RCT

Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis: the EASI-SWITCH RCT

Lower urinary tract symptoms in men: the TRIUMPH cluster RCT

A randomised, double blind, placebo-controlled trial of a two-week course of dexamethasone for adult patients with a symptomatic Chronic Subdural Haematoma (Dex-CSDH trial)

Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis

Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT

Thromboprophylaxis during pregnancy and the puerperium: a systematic review and economic evaluation to estimate the value of future research

Use of selective gut decontamination in critically ill children: PICnIC a pilot RCT and mixed-methods study

Clinical outcomes and adverse events of bariatric surgery in adults with severe obesity in Scotland: the SCOTS observational cohort study

Clinical and cost-effectiveness of an adapted intervention for preschoolers with moderate to severe intellectual disabilities displaying behaviours that challenge: the EPICC-ID RCT

Strategies used for childhood chronic functional constipation: the SUCCESS evidence synthesis

Abrocitinib, tralokinumab and upadacitinib for treating moderate-to-severe atopic dermatitis

Development and evaluation of a de-escalation training intervention in adult acute and forensic units: the EDITION systematic review and feasibility trial

Undertaking Studies Within A Trial to evaluate recruitment and retention strategies for randomised controlled trials: lessons learnt from the PROMETHEUS research programme

A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation

Explore our journals