Volume 20 (2016)

Clinical effectiveness and cost-effectiveness of surgical options for the management of anterior and/or posterior vaginal wall prolapse: two randomised controlled trials within a comprehensive cohort study results from the PROSPECT Study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 95
• Published:
  4 January 2017

The use of fibrin sealant during non-emergency surgery: a systematic review of evidence of benefits and harms

• Journal:
  Health Technology Assessment Volume: 20, Issue: 94
• Published:
  4 January 2017

PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term a cluster randomised controlled trial and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 93
• Published:
  22 December 2016

An observational study to assess if automated diabetic retinopathy image assessment software can replace one or more steps of manual imaging grading and to determine their cost-effectiveness

• Journal:
  Health Technology Assessment Volume: 20, Issue: 92
• Published:
  16 December 2016

The Men's Safer Sex project: intervention development and feasibility randomised controlled trial of an interactive digital intervention to increase condom use in men

• Journal:
  Health Technology Assessment Volume: 20, Issue: 91
• Published:
  14 December 2016

The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 90
• Published:
  7 December 2016

The second Randomised Evaluation of the Effectiveness, cost-effectiveness and Acceptability of Computerised Therapy (REEACT-2) trial: does the provision of telephone support enhance the effectiveness of computer-delivered cognitive behaviour therapy? A randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 89
• Published:
  5 December 2016

The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 88
• Published:
  5 December 2016

Placental growth factor (alone or in combination with soluble fms-like tyrosine kinase 1) as an aid to the assessment of women with suspected pre-eclampsia: systematic review and economic analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 87
• Published:
  5 December 2016

The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 86
• Published:
  2 December 2016

An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK

• Journal:
  Health Technology Assessment Volume: 20, Issue: 85
• Published:
  29 November 2016

Enhanced invitation methods and uptake of health checks in primary care: randomised controlled trial and cohort study using electronic health records

• Journal:
  Health Technology Assessment Volume: 20, Issue: 84
• Published:
  14 November 2016

Clinical effectiveness and cost-effectiveness of use of therapeutic monitoring of tumour necrosis factor alpha (TNF-a) inhibitors [LISA-TRACKER® enzyme-linked immunosorbent assay (ELISA) kits, TNF-a-Blocker ELISA kits and Promonitor® ELISA kits] versus standard care in patients with Crohn's disease: systematic reviews and economic modelling

• Journal:
  Health Technology Assessment Volume: 20, Issue: 83
• Published:
  14 November 2016

Concordance in diabetic foot ulceration: a cross-sectional study of agreement between wound swabbing and tissue sampling in infected ulcers

• Journal:
  Health Technology Assessment Volume: 20, Issue: 82
• Published:
  8 November 2016

Modelling disease progression in relapsing remitting onset multiple sclerosis using multilevel models applied to longitudinal data from two natural history cohorts and one treated cohort

• Journal:
  Health Technology Assessment Volume: 20, Issue: 81
• Published:
  3 November 2016

The Effectiveness, cost-effectiveness and acceptability of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual randomised balanced incomplete block trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 80
• Published:
  3 November 2016

Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme a randomised controlled trial and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 79
• Published:
  31 October 2016

A systematic review and economic evaluation of bisphosphonates for the prevention of fragility fractures

• Journal:
  Health Technology Assessment Volume: 20, Issue: 78
• Published:
  31 October 2016

Automated tests for diagnosing and monitoring cognitive impairment: a diagnostic accuracy review

• Journal:
  Health Technology Assessment Volume: 20, Issue: 77
• Published:
  20 October 2016

Models and applications for measuring the impact of health research: Update of a systematic review for the Health Technology Assessment Programme

• Journal:
  Health Technology Assessment Volume: 20, Issue: 76
• Published:
  20 October 2016

The Ankle Injury Management (AIM) trial: a pragmatic, multicentre, equivalence randomised controlled trial and economic evaluation comparing close contact casting with open surgical reduction and internal fixation in the treatment of unstable ankle fractures in patients aged over 60 years

• Journal:
  Health Technology Assessment Volume: 20, Issue: 75
• Published:
  12 October 2016

Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment

• Journal:
  Health Technology Assessment Volume: 20, Issue: 74
• Published:
  11 October 2016

An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 73
• Published:
  30 September 2016

UnderstaNding uptake of Immunisations in TravellIng aNd Gypsy communities (UNITING) A qualitative interview study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 72
• Published:
  29 September 2016

A randomised controlled trial to measure the effects and costs of a dental caries prevention regime for young children attending primary care dental services: the Northern Ireland Caries Prevention In Practice (NIC-PIP) trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 71
• Published:
  29 September 2016

Financial incentives to improve adherence to antipsychotic maintenance medication in non-adherent patients: a cluster randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 70
• Published:
  29 September 2016

The effectiveness, acceptability and cost-effectiveness of psychosocial interventions for maltreated children and adolescents: an evidence synthesis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 69
• Published:
  28 September 2016

A cluster randomised trial of strategies to increase cervical screening uptake at first invitation (STRATEGIC)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 68
• Published:
  19 September 2016

ImmunoCAP® ISAC and Microtest for multiplex allergen testing in people with difficult to manageallergic disease: a systematic review and cost analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 67
• Published:
  13 September 2016

A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 66
• Published:
  30 August 2016

Which method is best for the induction of labour? A systematic review, network meta-analysis and cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 65
• Published:
  30 August 2016

A randomised trial of the effect and cost-effectiveness of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with screen-detected type 2 diabetes: the Anglo Danish Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION-Europe) study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 64
• Published:
  30 August 2016

Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson's disease: a large pragmatic randomised controlled trial(PD REHAB)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 63
• Published:
  30 August 2016

Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model

• Journal:
  Health Technology Assessment Volume: 20, Issue: 62
• Published:
  30 August 2016

Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 61
• Published:
  24 August 2016

A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 60
• Published:
  15 August 2016

An evaluation of the effect of an angiotensin-converting enzyme inhibitor on the growth rate of small abdominal aortic aneurysms: a randomised placebo-controlled trial (AARDVARK)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 59
• Published:
  3 August 2016

VivaScope® 1500 and 3000 systems for detecting and monitoring skin lesions: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 58
• Published:
  2 August 2016

Can text messages increase safer sex behaviours in young people? Intervention development and pilot randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 57
• Published:
  1 August 2016

Cognitive behavioural therapy-based intervention to reduce fear of falling in older people: therapy development and randomised controlled trial the Strategies for Increasing Independence, Confidence and Energy (STRIDE) study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 56
• Published:
  1 August 2016

Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 55
• Published:
  1 August 2016

A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review

• Journal:
  Health Technology Assessment Volume: 20, Issue: 54
• Published:
  28 July 2016

TRAPEZE: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of chemotherapy with zoledronic acid, strontium-89, or both, in men with bony metastatic castration-refractory prostate cancer

• Journal:
  Health Technology Assessment Volume: 20, Issue: 53
• Published:
  18 July 2016

Psychoeducation with problem-solving (PEPS) therapy for adults with personality disorder: a pragmatic randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of a manualised intervention to improve social functioning

• Journal:
  Health Technology Assessment Volume: 20, Issue: 52
• Published:
  18 July 2016

The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness

• Journal:
  Health Technology Assessment Volume: 20, Issue: 51
• Published:
  11 July 2016

The feasibility of determining the effectiveness and cost-effectiveness of medication organisation devices compared with usual care for older people in a community setting: systematic review, stakeholder focus groups and feasibility randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 50
• Published:
  6 July 2016

BREATHER (PENTA 16) short-cycle therapy (SCT) (5 days on/2 days off) in young people with chronic human immunodeficiency virus infection: an open, randomised, parallel-group Phase II/III trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 49
• Published:
  4 July 2016

Comparing open and minimally invasive surgical procedures for Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer: the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 48
• Published:
  30 June 2016

The feasibility of a randomised controlled trial of physiotherapy for adults with joint hypermobility syndrome

• Journal:
  Health Technology Assessment Volume: 20, Issue: 47
• Published:
  30 June 2016

Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 46
• Published:
  28 June 2016

DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis a randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 45
• Published:
  28 June 2016

Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: pragmatic randomised Trial and economic evaluation (CONSTRUCT)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 44
• Published:
  21 June 2016

A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive compulsive disorder in children/adolescents and adults

• Journal:
  Health Technology Assessment Volume: 20, Issue: 43
• Published:
  15 June 2016

Neuraminidase inhibitors for influenza: a systematic review and meta- analysis of regulatory and mortality data

• Journal:
  Health Technology Assessment Volume: 20, Issue: 42
• Published:
  31 May 2016

PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 41
• Published:
  25 May 2016

The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer

• Journal:
  Health Technology Assessment Volume: 20, Issue: 40
• Published:
  24 May 2016

Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy (including a review of TA140 and TA262):clinical effectiveness systematic review and economic model

• Journal:
  Health Technology Assessment Volume: 20, Issue: 39
• Published:
  24 May 2016

Accurate diagnosis of latent tuberculosis in children, people who are immunocompromised or at risk from immunosuppression and recent arrivals from countries with a high incidence of tuberculosis: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 38
• Published:
  23 May 2016

A systematic review, evidence synthesis and meta-analysis of quantitative and qualitative studies evaluating the clinical effectiveness, the cost-effectiveness, safety and acceptability of interventions to prevent postnatal depression

• Journal:
  Health Technology Assessment Volume: 20, Issue: 37
• Published:
  16 May 2016

A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes

• Journal:
  Health Technology Assessment Volume: 20, Issue: 36
• Published:
  11 May 2016

Adalimumab, etanercept, infliximab,certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 35
• Published:
  4 May 2016

The clinical effectiveness and cost-effectiveness of abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 34
• Published:
  4 May 2016

Evaluating Acupuncture and Standard carE for pregnant women with Back pain (EASE Back):a feasibility study and pilot randomised trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 33
• Published:
  3 May 2016

UK FASHIoN: feasibility study of a randomised controlled trial of arthroscopic surgery for hip impingement compared with best conservative care

• Journal:
  Health Technology Assessment Volume: 20, Issue: 32
• Published:
  27 April 2016

Accuracy of fundus autofluorescence imaging for the diagnosis and monitoring of retinal conditions: a systematic review

• Journal:
  Health Technology Assessment Volume: 20, Issue: 31
• Published:
  26 April 2016

The clinical effectiveness and cost-effectiveness of heated humidified high-flow nasal cannula compared with usual care for preterm infants: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 30
• Published:
  25 April 2016

Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 29
• Published:
  19 April 2016

A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 28
• Published:
  19 April 2016

Does therapeutic writing help people with long-term conditions? Systematic review, realist synthesis and economic considerations

• Journal:
  Health Technology Assessment Volume: 20, Issue: 27
• Published:
  13 April 2016

The use of exploratory analyses within the National Institute for Health and Care Excellence single technology appraisal process: an evaluation and qualitative analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 26
• Published:
  6 April 2016

Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

• Journal:
  Health Technology Assessment Volume: 20, Issue: 25
• Published:
  4 April 2016

Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 24
• Published:
  4 April 2016

Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records

• Journal:
  Health Technology Assessment Volume: 20, Issue: 23
• Published:
  1 April 2016

The natural history of Chlamydia trachomatis infection in women: a multi parameter evidence synthesis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 22
• Published:
  24 March 2016

The Protease Inhibitor Monotherapy Versus Ongoing Triple Therapy (PIVOT) trial: a randomised controlled trial of a protease inhibitor monotherapy strategy for long-term management of human immunodeficiency virus infection

• Journal:
  Health Technology Assessment Volume: 20, Issue: 21
• Published:
  17 March 2016

Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): a randomised controlled trial with cost-effectiveness analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 20
• Published:
  16 March 2016

A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 19
• Published:
  2 March 2016

CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children

• Journal:
  Health Technology Assessment Volume: 20, Issue: 18
• Published:
  2 March 2016

Integrated sensor-augmented pump therapy systems [the MiniMed® Paradigm Veo system and the Vibe and G4® PLATINUM CGM (continuous glucose monitoring) system] for managing blood glucose levels in type 1 diabetes: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 17
• Published:
  2 March 2016

Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): a systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement

• Journal:
  Health Technology Assessment Volume: 20, Issue: 16
• Published:
  1 March 2016

An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 15
• Published:
  29 February 2016

Clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care (CADET): a cluster randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 14
• Published:
  24 February 2016

The effectiveness and cost-effectiveness of erythropoiesis-stimulating agents (epoetin and darbepoetin) for treating cancer treatment-induced anaemia (including review of technology appraisal no. 142): a systematic review and economic model

• Journal:
  Health Technology Assessment Volume: 20, Issue: 13
• Published:
  24 February 2016

Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 12
• Published:
  16 February 2016

Clinical effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia: a multicentre randomised controlled trial

• Journal:
  Health Technology Assessment Volume: 20, Issue: 11
• Published:
  15 February 2016

OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer

• Journal:
  Health Technology Assessment Volume: 20, Issue: 10
• Published:
  11 February 2016

Tumour necrosis factor-a inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 9
• Published:
  8 February 2016

Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study)

• Journal:
  Health Technology Assessment Volume: 20, Issue: 8
• Published:
  1 February 2016

Bladder ultrasound for diagnosing detrusor overactivity: test accuracy study and economic evaluation

• Journal:
  Health Technology Assessment Volume: 20, Issue: 7
• Published:
  26 January 2016

Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness components

• Journal:
  Health Technology Assessment Volume: 20, Issue: 6
• Published:
  20 January 2016

Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette Syndrome: A systematic review and qualitative analysis

• Journal:
  Health Technology Assessment Volume: 20, Issue: 4
• Published:
  20 January 2016

Improving outcomes for people in mental health crisis: a rapid synthesis of the evidence for available models of care

• Journal:
  Health Technology Assessment Volume: 20, Issue: 3
• Published:
  18 January 2016

Non-pharmacological treatments for stuttering in children and adults: a systematic review and evaluation of clinical effectiveness, and exploration of barriers to successful outcomes

• Journal:
  Health Technology Assessment Volume: 20, Issue: 2
• Published:
  18 January 2016

The head injury transportation straight to Neurosurgery (HITS-NS) randomised trial - a feasibility study

• Journal:
  Health Technology Assessment Volume: 20, Issue: 1
• Published:
  12 January 2016